Susan wrote:
Doug Freyburger wrote:

Drop low carb enough long enough and thyroid reduces T3 output.

Actually, "long enough" is the first 24 or 27 hours. And you don't have
to drop carbs, it happens with very low calorie consumption, too.

If the goal is basal metabolism reduction, then the goal is deliberately
triggering starvation mode and a stall. Not the usual goal for a low
carb dieter. The two week time scale of the usual T3 adjustment of
ketosis levels isn't enough for the longevity trigger.

That
reduces basal metabolism. Lower metabolism is associated with better
lonevity. In rats and mice anyways it looks like super low carb is the
macro-nutrient most responsible for the long life of underfed test
subjects. Might work in humans.

Super low calorie, leading to discussion of caloric restriction for
longevity. Low carb may be helpful, too, but very low consumption of
calories seems to be linked to longevity, too.

The original observation was with low calorie. Doing it low carb is the
refinement. It's been done to rats, worms, whatever. Not to humans.

Going to 20 for life might well extend life as long as all of the
non-carb nutrients are handled correctly.