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#121
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Keep in mind that lipid abnormalities are elevated grossly in people
who are overweight. If they lose the weight then they become more normal in lipids. They are the same individual in terms of genetics but the variable being the obesity. It is not all derived from diet but from the abnormal physiology associated with being overweight ie "metabolic syndrome". In fact it would perfectly explained all the confusion about cholesterol. Being overweight and Mets is THE cause. High cholesterol (or bad TC/HDL) is just indication of BMI and Mets. You are free to see what you want to see. If you ever get a heart attack then you might see things differently. Statins are not the final answer and things will change. Agree. Mirek |
#122
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Keep in mind that lipid abnormalities are elevated grossly in people
who are overweight. If they lose the weight then they become more normal in lipids. They are the same individual in terms of genetics but the variable being the obesity. It is not all derived from diet but from the abnormal physiology associated with being overweight ie "metabolic syndrome". In fact it would perfectly explained all the confusion about cholesterol. Being overweight and Mets is THE cause. High cholesterol (or bad TC/HDL) is just indication of BMI and Mets. You are free to see what you want to see. If you ever get a heart attack then you might see things differently. Statins are not the final answer and things will change. Agree. Mirek |
#123
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"Mirek Fidler" wrote in message ... Well, as far as I am concerned saturated fat and cholesterol causes heart disease. It always amazes me that people will pour bacon grease into a cup and let it harden because they don't want to clog their pipes yet they don't see the correlation with the clogging of their arteries. Well, you are making classical mistake - applying your kitchen experience to human body. But it is not how it works: Fat that gets absorbed in intestines does NOT goes directly too blood. Instead it is packed and distributed in particles called chylomicrons - and nobody never found chylomicrons to be harmful to arteries - for simple reason - they are too big to penetrate and/or damage endothelium. The fat gets stored and body mass fat does indeed have consequences in terms of breast cancer. Now carbs are converted to saturated fat in liver and transported in VLDL particles. After loosing its fat contents, VLDL become LDL - so called bad cholesterol. Now amount of insulin secreted probably affects LDL size. Smaller LDL is supposed to be more likely to penetrate endothelium and oxidize and plague to grow. Mirek |
#124
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"Mirek Fidler" wrote in message ... 2) Lowering cholesterol by means of diet does not work Who said it has to be dietary cholesterol that is the sole problem. The body makes cholesterol on it's own and it is a genetic misprint in the balance. Look at this logic. Glucose is not the problem in type I diabetes because a low carb diet does not cure and people die. I think he speaks about lowering LDL by low-fat diet. Not dietary cholesterol. And, BTW, IMO research consistetly shows why it is so: while low-fat decreases LDL, it also decreases LDL particle size. I think you have to make a big distinction of normal versus abnormal physiology and any study of an individual that is normal versus one who is abnormal will not be the same. Insulin response is different in a diabetic, metabolic syndrome vs a normal individual. The bottom line is that one is really only quessing to what extend one can extrapolate to ones self the degree of dietary influences. 3) Lowering cholesterol by means of diet and drugs does not reduce overall mortality. There are good reasons to suspect that statins also stimulate cancer, which takes longer to find out than any of the studies took. There are many studies about lowering cholesterol and the benefits. You will There are in fact many studies about statin benefits. And some of them in fact show that benefits are unrelated to cholesterol lowering effects. There are very little studies showing benefits of other cholesterol lowering drugs/techniques. Mirek Statins don't work for everyone and that is the reason where other drugs are out there. |
#125
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"Mirek Fidler" wrote in message ... 2) Lowering cholesterol by means of diet does not work Who said it has to be dietary cholesterol that is the sole problem. The body makes cholesterol on it's own and it is a genetic misprint in the balance. Look at this logic. Glucose is not the problem in type I diabetes because a low carb diet does not cure and people die. I think he speaks about lowering LDL by low-fat diet. Not dietary cholesterol. And, BTW, IMO research consistetly shows why it is so: while low-fat decreases LDL, it also decreases LDL particle size. I think you have to make a big distinction of normal versus abnormal physiology and any study of an individual that is normal versus one who is abnormal will not be the same. Insulin response is different in a diabetic, metabolic syndrome vs a normal individual. The bottom line is that one is really only quessing to what extend one can extrapolate to ones self the degree of dietary influences. 3) Lowering cholesterol by means of diet and drugs does not reduce overall mortality. There are good reasons to suspect that statins also stimulate cancer, which takes longer to find out than any of the studies took. There are many studies about lowering cholesterol and the benefits. You will There are in fact many studies about statin benefits. And some of them in fact show that benefits are unrelated to cholesterol lowering effects. There are very little studies showing benefits of other cholesterol lowering drugs/techniques. Mirek Statins don't work for everyone and that is the reason where other drugs are out there. |
#126
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Well, as far as I am concerned saturated fat and cholesterol
causes heart disease. It always amazes me that people will pour bacon grease into a cup and let it harden because they don't want to clog their pipes yet they don't see the correlation with the clogging of their arteries. Well, you are making classical mistake - applying your kitchen experience to human body. But it is not how it works: Fat that gets absorbed in intestines does NOT goes directly too blood. Instead it is packed and distributed in particles called chylomicrons - and nobody never found chylomicrons to be harmful to arteries - for simple reason - they are too big to penetrate and/or damage endothelium. The fat gets stored and body mass fat does indeed have consequences in terms of breast cancer. Yes, but body mass depends on total energy consumed (absorbed), not on macronutient ratios. (Well, some of fellow low-carbers would even swear that fat has metabolic (dis)advantage, but I would not go so far). You seem to be making classical low-fat's dieter mistake that only fat makes you fat. BTW, if breast cancer concerns you so much, recent research found clear association of breast cancer with high carb diet.... Mirek |
#127
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And, BTW, IMO research consistetly shows why it is so: while low-fat
decreases LDL, it also decreases LDL particle size. I think you have to make a big distinction of normal versus abnormal physiology and any study of an individual that is normal versus one who is abnormal will not be the same. Insulin response is different in a diabetic, metabolic syndrome vs a normal individual. The bottom line is that one is really only quessing to what extend one can extrapolate to ones self the degree of dietary influences. Well, but it is already e.g. known that people with large LDL (pattern A - 75% of population with low average CVD risk) are converted to small LDL pattern by low-fat diet. So 75% of people might be in fact damaged by low-fat. Mirek |
#128
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And, BTW, IMO research consistetly shows why it is so: while low-fat
decreases LDL, it also decreases LDL particle size. I think you have to make a big distinction of normal versus abnormal physiology and any study of an individual that is normal versus one who is abnormal will not be the same. Insulin response is different in a diabetic, metabolic syndrome vs a normal individual. The bottom line is that one is really only quessing to what extend one can extrapolate to ones self the degree of dietary influences. Well, but it is already e.g. known that people with large LDL (pattern A - 75% of population with low average CVD risk) are converted to small LDL pattern by low-fat diet. So 75% of people might be in fact damaged by low-fat. Mirek |
#129
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"Mirek Fidler" wrote in message ...
Insulin caused by overconsumption of carbohydrates. I see so insulin is clogging peoples arteries hmm..... Well, some hints for you: Why Type2 diabetics have much higher incidence of coronary? You can also try to google some relationships between carbs, TG, HDL, LDL density and oxLDL. Another hint: what they did to that mice that outlived its lifespan by year? Low-carb might not be ideal, but insulin (metabolic syndrome) is at least one of biggest contributors to heart disease. Mirek The way I have seen metabolic syndrome described is by lumping a group of risk factors like high blood pressure, high cholesterol and insulin resistance and calling it syndrome X, which can lead to heart disease obesity and diabetes. Many people have the causes, risk factors, and effects all mixed up. I would suggest that heart disease as well as the conditions that make up the so called metabolic syndrome are actually just symptoms of insulin resistance which very from person to person depending on the severity of insulin resistance, which is the true cause of the many degenerative conditions. This is what so many people fail to understand. It really is very simple. The medical establishment however would have us believe things are immensely complex and out of our control. This is understandable considering it serves to benefit them. For the same reason dentists and orthodontists do not tell you what a simple matter it is to remain free of cavities and gum disease for your whole life as well as insure that your children will be born with straight teeth. Just imagine what that would do to their profession?? It could be wiped from the face of the earth. Does anyone really have any delusions about whether they would allow that to happen if they had any say about it. |
#130
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"Mirek Fidler" wrote in message ...
Insulin caused by overconsumption of carbohydrates. I see so insulin is clogging peoples arteries hmm..... Well, some hints for you: Why Type2 diabetics have much higher incidence of coronary? You can also try to google some relationships between carbs, TG, HDL, LDL density and oxLDL. Another hint: what they did to that mice that outlived its lifespan by year? Low-carb might not be ideal, but insulin (metabolic syndrome) is at least one of biggest contributors to heart disease. Mirek The way I have seen metabolic syndrome described is by lumping a group of risk factors like high blood pressure, high cholesterol and insulin resistance and calling it syndrome X, which can lead to heart disease obesity and diabetes. Many people have the causes, risk factors, and effects all mixed up. I would suggest that heart disease as well as the conditions that make up the so called metabolic syndrome are actually just symptoms of insulin resistance which very from person to person depending on the severity of insulin resistance, which is the true cause of the many degenerative conditions. This is what so many people fail to understand. It really is very simple. The medical establishment however would have us believe things are immensely complex and out of our control. This is understandable considering it serves to benefit them. For the same reason dentists and orthodontists do not tell you what a simple matter it is to remain free of cavities and gum disease for your whole life as well as insure that your children will be born with straight teeth. Just imagine what that would do to their profession?? It could be wiped from the face of the earth. Does anyone really have any delusions about whether they would allow that to happen if they had any say about it. |
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