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UN FAO & WHO approve Steviol glycosides as sweetener June 2004, imports to UK no longer blocked: Martini: Murray 2004.10.17 rmforall



 
 
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Old October 17th, 2004, 05:13 PM
Rich Murray
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Default UN FAO & WHO approve Steviol glycosides as sweetener June 2004, imports to UK no longer blocked: Martini: Murray 2004.10.17 rmforall


http://groups.yahoo.com/group/aspartameNM/message/1122
UN FAO & WHO approve Steviol glycosides as sweetener June 2004, imports to
UK no longer blocked: Martini: Murray 2004.10.17 rmforall

[ Comments by Rich Murray are in square brackets. ]
************************************************** **************

[ The first of 25 items in http://www.google.com
for search on "WHO Expert Committee on Food Additives", Steviol ]

http://www.freestevia.de/63%20th%20JECFA%20meeting.htm

JECFA/63/SC Food and Agriculture Organization of the United Nations
World Health Organization

JOINT FAO/WHO EXPERT COMMITTEE ON FOOD ADDITIVES
Sixty-third meeting Geneva, 8-17 June 2004

SUMMARY AND CONCLUSIONS
A meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)
was held in Geneva, Switzerland, from 8 to 17 June 2004.

The purpose of the meeting was to evaluate certain food additives and
ingredients, flavouring agents, and a natural constituent of food.

Dr John B. Larsen, Division of Toxicology and Risk Assessment, Danish
Institute of Food and Veterinary Research, Søborg, Denmark, served as
Chairman and
[ ]

Mrs Inge Meyland, Danish Institute of Food and Veterinary Research, Søborg,
Denmark, served as Vice-Chairman.
[ Inge Meyland (Representative for Food Directorate)
Institut for Fødevareundersøgelser og Ernæring
Fødevaredirektoratet Mørkhøj Bygade 19 2860 Søborg
Telephone: 33 95 64 04 Telefax: 33 95 66 19
]

Dr Manfred Luetzow, Food Quality and Standards Service, Food and Nutrition
Division, Food and Agriculture Organization of the United Nations, and
[ Food and Agriculture Organization of the United Nations, Viale delle
Terme di Caracalla, 00100, Rome, Italy.
]

Dr Angelika Tritscher, International Programme on Chemical Safety, World
Health Organization, served as joint secretaries. [
]

The present meeting was the sixty-third in a series of similar meetings. The
tasks before the Committee were (a) to elaborate further principles for
evaluating the safety of food additives; (b) to evaluate certain food
additives, ingredients, and flavouring agents; (c) to review and prepare
specifications for selected food additives and flavouring agents; (d) to
evaluate a natural constituent of food.

The report of the meeting will appear in the WHO Technical Report Series.
Its presentation will be similar to that of previous reports, namely,
general considerations, comments on specific substances, and recommendations
for future work.

An annex will include detailed tables (similar to the tables in this report)
summarizing the main conclusions of the Committee in terms of acceptable
daily intakes (ADIs) and other toxicological recommendations.

Information on specifications for the identity and purity of certain food
additives examined by the Committee will also be included.

The participants in the meeting are listed in Annex 1.

Further information required or desired is listed in Annex 2.

General considerations, that contain information that the Committee would
like to disseminate quickly are included in Annex 3.

Toxicological monographs or monograph addenda on most of the substances that
were considered will be published in WHO Food Additives Series No. 54.

New and revised specifications for the identity and purity of the compounds
will be published in FAO Food and Nutrition Paper Series 52, Addendum 12.

More information on the work of the Joint FAO/WHO Expert
Committee on Food Additives (JECFA) is available at:

www.fao.org/es/esn/jecfa/index_en.stm

www.who.int/pcs/jecfa/jecfa.htm

Toxicological recommendations and information on specifications

1. Food additives and ingredients evaluated toxicologically

Food additive Specifications a)
Acceptable daily intake (ADI) and other toxicological
recommendations


Steviol glycosides N, T 0 to 2 mg/kg body weight
(temporary)
[ Up to 120 mg for 60-kg person ]

a) N: new specifications prepared T: tentative specifications

Steviol glycosides

The Committee required additional information by 2007, on the
pharmacological effects of steviol glycosides in humans.

These studies should involve repeated exposure to dietary and therapeutic
doses, in normotensive and hypotensive individuals and in insulin-dependent
and insulinindependent diabetics.

In order to be able to remove the tentative designation from the
specifications, further information for commercially available products is
required on:

Analytical data on distribution and concentrations of all component
steviol glycosides, including those that are not identified in these
tentative specifications.

Method of analysis for the determination of all component steviol
glycosides, including those that are not identified in these tentative
specifications;

The nature and concentration of the fractions that do not contain steviol
glycosides.

The quantities of residual solvents from isolation and purification steps
of the manufacturing process.

The hydrolytic stability of the steviol glycosides in acidic foods and
beverages.

[ Wouldn't it it wonderful if similar exacting data were required for
aspartame, neotame, sucralose, Ace-K, etc? ]

Herausgegeben von: Förderkreis "Stevia für Alle", Ansprechpartner: Frau
Margitta Holly, Scharnhorst Str.1, D-65195 Wiesbaden, BRD, Fax 0049 611-940
6839.
Sämtliche Ausführungen in dieser Darstellung unterliegen den Bestimmungen
des Copyrights und des Haftungsausschluss. Die Wiedergabe ist vorbehaltlich
anderslautender Bestimmungen NICHT gestattet. "Stevia für Alle" übernimmt
keinerlei Verantwortung oder Haftung für die Angaben in dieser Darstellung.
Drucken
************************************************** ***************

http://www.cspinet.org/foodsafety/additives_stevia.html

Previous stevia history by anti-stevia, pro-aspartame industry dominated
group
************************************************** ***************

From: "Dr. Betty Martini"
To: "Activist List-yahoogroups.com"
Subject: [Aspartame Support] Immediate Release:
Stevia No Longer Banned in Europe --
Aspartame: Rats Jump NutraShip.
Date: Saturday, October 16, 2004 7:56 PM

A meeting in Geneva June 8 - 17, of the Joint FAQ/WHO Expert Committee on
Food Additives was held to evaluate certain food additives, ingredients,
and flavouring agents.

It was decided that Steviol glycosides be approved. and orders to England
are no longer being confiscated.
A study is pending to make sure it doesn't lower blood sugar in
non-diabetics.
Stevia has always been known to help in the metabolism of sugar, thus being
beneficial to diabetics.

Diabetic specialist, H. J. Roberts, M.D., FACP, says aspartame
(NutraSweet/Equal/Spoonful, E951, Canderel) can actually precipitate
diabetes, aggravates and simulates diabetic retinopathy and neuropathy,
causes diabetics to go into convulsions, and even interacts with
insulin. No wonder we have an epidemic of diabetes. Read Larry Hagman's
comments on http://www.dorway.com on how Stevia saved his life when he
became diabetic after a liver transplant.

Many may remember that the reinvestigation of Stevia was an amendment to
Parliament.

On September 15, 2004, filed in the US District Court for the Northern
District of California, were racketeering (RICO) charges against
NutraSweet, their spin doctor Dr. Robert Moser, the American Diabetes
Association and Monsanto Chemical Company. For the whole story and
complete lawsuit see the racketeering banner on http://www.wnho.net

Click to see Attorney James Turner, Washington, D.C. explaining how Donald
Rumsfeld got aspartame approved when the FDA said NO!
http://www.soundandfury.tv/Pages/Rumsfeld.html

The NutraSweet Titanic has hit the iceberg. Pepsi to remove aspartame

From the Atlanta Journal Constitution 9/21/2004

FOOD/BEVERAGES: Pepsi plans new products

Pepsico is reportedly planning a trio of new products next year. Pepsi One,
which was introduced in 1998 using a blend of sweeteners ace-K and
aspartame, will be reformulated with sucralose next year, Beverage Digest
said, citing bottlers and unidentified sources.

Sucralose is marketed by Johnson & Johnson's McNeil Nutritionals unit as
Splenda. "Sucralose has become very popular with consumers, and having a
diet cola sweetened with that sweetener could prove to have a great deal of
consumer appeal," said Beverage Digest Editor John Sicher.

Pepsi also is planning to introduce a sparkling Aquafina and a no-calorie or
low-calorie flavored water, possibly called Splash, according to the
industry publication.

While it is good news the deadly neurotoxic drug aspartame is being
withdrawn, it should be of great concern to the public that Sucralose or
Splenda is a chlorinated hydrocarbon.
H. J. Roberts, M.D. says it can trigger autoimmune disease.
He discusses this in his medical text, Aspartame Disease: An Ignored
Epidemic, http://www.sunsentpress.com or 800-827-7991 .

There are several articles about sucralose or Splenda, and
the original research on http://www.wnho.net click on aspartame.

Dr. Betty Martini, Founder, Mission Possible International, 9270 River Club
Parkway, Duluth, Georgia 30097 770-242-2599
http://www.wnho.net and http://www.dorway.com

Aspartame Toxicity Information Center http://www.holisticmed.com/aspartame

PLEASE TRY AND RECRUIT MEMBERS - SEND THEM TO
http://groups.yahoo.com/group/aspartame/

PRINT OUT THIS FLIER AND HAND IT OUT TO PEOPLE:
http://www.ojinaga.com/aspartame/

CHECK OUT OUR WEBSITE!! http://presidiotex.com/aspartame

FREE ASPARTAME BUMPER STICKER http://ojinaga.com/bumperstickers/freesticker/

to subscribe to this list, send a blank e-mail to:


Our chat room is at
http://pub43.bravenet.com/chat/show.php/3648148879

To visit your group on the web, go to:
http://groups.yahoo.com/group/aspartame/

To unsubscribe from this group, send an email to:

************************************************** ***************

http://groups.yahoo.com/group/aspartameNM/message/989 On 2003.04.10
the European Union Parliament voted 440 to 20 to approve sucralose,
limit cyclamates & reevaluate aspartame & stevia: Murray 2003.04.12 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1084
26 stevia safety abstracts since 1993: aspartame vs stevia debate on
alt.support.diabetes, George Schmidt, OD: Murray 2004.05.25 rmforall

Geuns_phytochemistry_stevioside.pdf
Phytochemistry. 2003 Nov; 64(5): 913-21.
Stevioside.
Geuns JM.
Laboratory of Plant Physiology, Catholic University of Leuven, Kasteelpark
Arenberg 31, B 3001 Leuven, Belgium.
* Tel.: +32-16-321510; fax: +32-16-321509.
E-mail address:
(J.M.C. Geuns).
Kasteelpark Arenberg 31, 3001 Heverlee, Belgium
http://www.kuleuven.ac.be/bio/biofys/
http://www.kuleuven.ac.be/bio/biofys/Plantfys_e.htm English
http://www.kuleuven.ac.be/bio/biofys/ESC/ESC.htm European Stevia Center

Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana
(Bertoni) Bertoni.
The literature about Stevia, the occurrence of its sweeteners, their
biosynthetic pathway and toxicological aspects are discussed.
Injection experiments or perfusion experiments of organs are considered as
not relevant for the use of Stevia or stevioside as food, and therefore
these studies are not included in this review.
The metabolism of stevioside is discussed in relation with the possible
formation of steviol.
Different mutagenicity studies as well as studies on carcinogenicity are
discussed. Acute and subacute toxicity studies revealed a very low toxicity
of Stevia and stevioside.
Fertility and teratogenicity studies are discussed as well as the effects on
the bio-availability of other nutrients in the diet.
The conclusion is that Stevia and stevioside are safe when used as a
sweetener. It is suited for both diabetics, and PKU patients, as well as for
obese persons intending to lose weight by avoiding sugar supplements in the
diet.
No allergic reactions to it seem to exist.
Publication Types: Review Review Literature PMID: 14561506

http://groups.yahoo.com/group/aspartameNM/message/934
24 recent formaldehyde toxicity [Comet assay] reports:
Murray 2002.12.31 rmforall

http://groups.yahoo.com/group/aspartameNM/message/935
Comet assay finds DNA damage from sucralose, cyclamate, saccharin in
mice: Sasaki YF & Tsuda S Aug 2002: Murray 2003.01.01 rmforall
[ Also borderline evidence, in this pilot study of 39 food additives,
using test groups of 4 mice, for DNA damage for stomach, colon,
liver, bladder, and lung 3 hr after oral dose of 2000 mg/kg aspartame --
a very high dose. Methanol is the only component of aspartame that can lead
to DNA damage. ]

http://groups.yahoo.com/group/aspartameNM/message/961
genotoxins, Comet assay in mice: Ace-K, stevia fine; aspartame poor;
sucralose, cyclamate, saccharin bad: Y.F. Sasaki Aug 2002:
Murray 2003.01.27 rmforall [A detailed look at the data] ]

J Toxicol Sci. 2002 Dec; 27 Suppl 1: 1-8.
[Genotoxicity studies of stevia extract and steviol by the comet assay]
[Article in Japanese]
Sekihashi K, Saitoh H, Sasaki Y.
Safety Research Institute for Chemical Compounds Co., Ltd., 363-24 Shin-ei,
Kiyota-ku, Sapporo 004-0839, Japan.

The genotoxicity of steviol, a metabolite of stevia extract, was evaluated
for its genotoxic potential using the comet assay.
In an in vitro study, steviol at 62.5, 125, 250, and 500 micrograms/ml did
not damage the nuclear DNA of TK6 and WTK1 cells in the presence
and absence of S9 mix.
In vivo studies of steviol were conducted by two independent organizations.
Mice were sacrificed 3 and 24 hr after one oral administration of steviol at
250, 500, 1000, and 2000 mg/kg.
DNA damage in multiple mouse organs was measured by the comet assay as
modified by us.
After oral treatment, stomach, colon, liver, kidney and testis DNA were not
damaged.
The in vivo genotoxicity of stevia extract was also evaluated for its
genotoxic potential using the comet assay.
Mice were sacrificed 3 and 24 hr after oral administration of stevia extract
at 250, 500, 1000, and 2000 mg/kg.
Stomach, colon and liver DNA were not damaged.
As all studies showed negative responses, stevia extract and steviol are
concluded to not have DNA-damaging activity in cultured cells and mouse
organs. PMID: 12533916

http://groups.yahoo.com/group/aspartameNM/message/1117
Aspartame and its effects on health, Michael E.J. Lean, Catherine R. Hankey,
Glasgow UK, British Medical Journal: 11% methanol component of aspartame,
and same level of methanol in dark wines and liquors is turned into
formaldehyde and formic acid, the main cause of chronic hangover symptoms:
Murray 2004.10.09 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1120
5 critical Rapid Responses to Aspartame and its effects on health, Michael E
J Lean and Catherine R Hankey, BMJ 2004; 329: 755-756: Murray 2004.10.07
rmforall

http://groups.yahoo.com/group/aspartameNM/message/1114
review of sweeteners 2004, Weihrauch MR, Diehl V: formaldehyde from 11%
methanol component of aspartame, methanol in dark wines and liquors,
fermentation of fruits in colon, also smoke, new buildings, furniture,
drapes, carpets, personal products: available database from Harvard Nurses'
Health Study II of 91,249 women in 1991-1999: Murray 2004.09.18 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1108
faults in 1999 July EPA 468-page formaldehyde profile:
Elzbieta Skrzydlewska PhD, Assc. Prof., Medical U. of Bialystok, Poland,
abstracts -- ethanol, methanol, formaldehyde, formic acid, acetaldehyde,
lipid peroxidation, green tea, aging, Lyme disease:
Murray 2004.08.08 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1109
Toxicological Profile for Formaldehyde 1/4 plain text, start to 111 of 468
pages USA DHHS PHS ATSDR 1999 July: Murray 2004.08.30 rmforall
************************************************** *************

http://groups.yahoo.com/group/aspartameNM/message/1016
President Bush & formaldehyde (aspartame) toxicity: Ramazzini Foundation
carcinogenicity results Dec 2002: Soffritti: Murray 2003.08.03 rmforall

p. 88 "The sweetening agent aspartame hydrolyzes in the gastrointestinal
tract to become free methyl alcohol, which is metabolized in the liver
to formaldehyde, formic acid, and CO2. (11)"
Medinsky MA & Dorman DC. 1994; Assessing risks of low-level
methanol exposure. CIIT Act. 14: 1-7.

Ann N Y Acad Sci. 2002 Dec; 982: 87-105.
Results of long-term experimental studies on the carcinogenicity of
formaldehyde and acetaldehyde in rats.
Soffritti M, Belpoggi F, Lambertin L, Lauriola M, Padovani M, Maltoni C.
Cancer Research Center, European Ramazzini Foundation for Oncology and
Environmental Sciences, Bologna, Italy.

Formaldehyde was administered for 104 weeks in drinking water supplied
ad libitum at concentrations of 1500, 1000, 500, 100, 50, 10, or 0 mg/L
to groups of 50 male and 50 female Sprague-Dawley rats beginning at
seven weeks of age.
Control animals (100 males and 100 females) received tap water only.
Acetaldehyde was administered to 50 male and 50 female Sprague-Dawley
rats beginning at six weeks of age at concentrations of 2,500, 1,500,
500, 250, 50, or 0 mg/L.
Animals were kept under observation until spontaneous death.
Formaldehyde and acetaldehyde were found to produce an increase in total
malignant tumors in the treated groups and showed specific carcinogenic
effects on various organs and tissues. PMID: 12562630

Ann N Y Acad Sci. 2002 Dec; 982: 46-69.

Results of long-term experimental studies on the carcinogenicity of
methyl alcohol and ethyl alcohol in rats.
Soffritti M, Belpoggi F, Cevolani D, Guarino M, Padovani M, Maltoni C.
Cancer Research Center, European Ramazzini Foundation for Oncology and
Environmental Sciences, Bologna, Italy.


Methyl alcohol was administered in drinking water supplied ad libitum at
doses of 20,000, 5,000, 500, or 0 ppm to groups of male and female
Sprague-Dawley rats 8 weeks old at the start of the experiment.
Animals were kept under observation until spontaneous death.
Ethyl alcohol was administered by ingestion in drinking water at a
concentration of 10% or 0% supplied ad libitum to groups of male and
female Sprague-Dawley rats; breeders and offspring were included in the
experiment.
Treatment started at 39 weeks of age (breeders), 7 days before mating,
or from embryo life (offspring) and lasted until their spontaneous death.
Under tested experimental conditions, methyl alcohol and ethyl alcohol
were demonstrated to be carcinogenic for various organs and tissues.
They must also be considered multipotential carcinogenic agents.
In addition to causing other tumors, ethyl alcohol induced malignant
tumors of the oral cavity, tongue, and lips.
These sites have been shown to be target organs in man by epidemiologic
studies. Publication Types: Review Review, Tutorial PMID: 12562628

Surely the authors deliberately emphasized that aspartame is well-known
to be a source of formaldehyde, which is an extremely potent, cumulative
toxin, with complex, multiple effects on all tissues and organs.

This is even more significant, considering that they have already tested
aspartame, but not yet released the results:

p. 29-32 Table 1: The Ramazzinni Foundation Cancer Program
Project of [200] Long-Term Carcinogenicity Bioassays: Agents Studied

No. No. of Bioassays Species No. Route of Exposure
108. "Coca-Cola" 4 Rat 1,999 Ingestion, Transplantal Route
109. "Pepsi-Cola" 1 Rat 400 Ingestion
110. Sucrose 1 Rat 400 Ingestion
111. Caffeine 1 Rat 800 Ingestion
112. Aspartame 1 Rat 1,800 Ingestion

http://members.nyas.org/events/confe...f_02_0429.html
Soffritti said that Coca-Cola showed no carcinogenicity.

It may be time to disclose these important aspartame results.
************************************************** *************

Poor memory is one of the main early complaints of aspartame reactors, who
are often people who use over 6 cans ( 2 L) diet soda daily for years.

The 12 experimental rats in this recent economical, focused pilot study by
McConnaughey M et al (2004 May), drank a comparable level for 4 months,
about 13% of a 30-month lifespan. It is an excellent introduction to the
main issues.

Only after 3 months did the 12 aspartame rats show almost a doubling of time
to run a single-choice maze.

At 4 months, there was almost another doubling of delay: "...two of the
treated rats even went to the wrong side of the T-maze, totally forgetting
where the reward was." These are very powerful, worrisome results.

There were highly significant, neurologically relevant changes in certain
brain receptor densities, and changes in brain chemistry.

With 70 citations, the relevant scientific literature is well summarized.
Many other studies, often industry funded, often used single doses or
too short durations of exposure, along with lower doses, thus rarely proving
memory deficits.

The funding source for this extremely valuable study is not given.
It used a team of talented high school students.

The fact that certain brain receptor densitities increased, and that memory
deficit increase took 3 months to be significant, may reflect the paradox of
hormesis, the complex ability of organisms to make themselves stronger in
response to low levels of toxins:

http://groups.yahoo.com/group/aspartameNM/message/1088
Murray, full plain text & critique:
chronic aspartame in rats affects memory, brain cholinergic receptors, and
brain chemistry, Christian B, McConnaughey M et al, 2004 May:
2004.06.05 rmforall

Pharmacol Biochem Behav. 2004 May; 78(1): 121-7.
Chronic aspartame affects T-maze performance, brain cholinergic receptors
and Na(+),K(+)-ATPase in rats.
Christian B, McConnaughey K, Bethea E, Brantley S, Coffey A, Hammond L,
Harrell S, Metcalf K, Muehlenbein D, Spruill W, Brinson L, McConnaughey M.
Department of Pharmacology, Brody School of Medicine, East Carolina
University, Greenville, NC 27858, USA;
North Carolina School of Science and Mathematics, Durham, NC 27811.
http://www.ecu.edu/pharmacology/facu...onnaughey.html
Mona M. McConnaughey, Ph.D. Research Assistant Professor
Department: PHARMACOLOGY & TOXICOLOGY
Office: Brody Medical Science 6E-120A 252-744-2756


This study demonstrated that chronic aspartame consumption in rats can lead
to altered T-maze performance and increased muscarinic cholinergic receptor
densities in certain brain regions.
Control and treated rats were trained in a T-maze to a particular side and
then periodically tested to see how well they retained the learned response.
Rats that had received aspartame (250 mg/kg/day) in the drinking water for 3
or 4 months showed a significant increase in time to reach the reward in the
T-maze, suggesting a possible effect on memory due to the artificial
sweetener. Using [(3)H]quinuclidinyl benzilate (QNB) (1 nM) to label
muscarinic cholinergic receptors and atropine (10(-6) M) to determine
nonspecific binding in whole-brain preparations,
aspartame-treated rats showed a 31% increase in receptor numbers when
compared to controls.
In aspartame-treated rats, there was a significant increase in muscarinic
receptor densities in the frontal cortex, midcortex, posterior cortex,
hippocampus, hypothalamus and cerebellum of 80%, 60%, 61%, 65%,
66% and 60%, respectively.
The midbrain was the only area where preparations from aspartame-treated
rats showed a significant increase in Na(+),K(+)-ATPase activity.
It can be concluded from these data that long-term consumption of aspartame
can affect T-maze performance in rats and alter receptor densities or
enzymes in brain. PMID: 15159141
************************************************** *************

http://www.dorway.com/tldaddic.html 5-page review
Roberts HJ Aspartame (NutraSweet) addiction.
Townsend Letter 2000 Jan;
http://www.sunsentpress.com/
Sunshine Sentinel Press P.O.Box 17799 West Palm Beach, FL 33416
800-814-9800 561-588-7628 561-547-8008 fax

http://groups.yahoo.com/group/aspartameNM/message/669
1038-page medical text "Aspartame Disease: An Ignored Epidemic"
published May 30 2001 $ 60.00 postpaid data from 1200 cases
available at http://www.amazon.com
over 600 references from standard medical research

http://groups.yahoo.com/group/aspartameNM/message/790
Moseley: review Roberts "Aspartame Disease: An Ignored Epidemic":
Murray 2002.02.07 rmforall

Roberts, Hyman J., 1924- ,
Useful insights for diagnosis, treatment and public heath: an updated
anthology of original research, 2002, 798 pages,
aspartame disease, pages 627-685, 778-780

http://groups.yahoo.com/group/aspartameNM/message/859
Roberts: the life work of a brilliant clinician: aspartame toxicity:
Murray 2002.08.02 rmforall
************************************************** *************

http://groups.yahoo.com/group/aspartameNM/message/1018
aspartame toxicity coverup increases danger of corporate meltdown:
Michael C. Carakostas of Coca-Cola: Murray 2003.08.11 rmforall
http://www.isrtp.org/new_members/members1.htm
The International Society of Regulatory Toxicology and Pharmacology
Carakostas, Michael C., DVM, PhD Director/Scientific & Regulatory
Affairs The Coca-Cola Company PO Drawer 1734 Atlanta, GA 30301
T. 404/676-4234 F. 404/676-7166 E-mail:
http://www2.coca-cola.com/ourcompany...aspartame.html [photo]
Aspartame: The world agrees it's safe By Michael Carakostas, DVM, PhD
Director, Scientific and Regulatory Affairs, Coca-Cola

It is commendable that Carakostas mentions the core problem, albeit
disparagingly, and overlaid with multiple untruths: "During digestion,
aspartame yields a very small amount of methanol-- as do many other food
substances. The body converts this methanol to formaldehyde, which is
instantly converted to formate. Formate is quickly eliminated as carbon
dioxide and water."

Carakostas deceptively make claims, unsupported by research, that the amount
of methanol from aspartame is "very small", that many foods release as much,
and that little of the inevitable formaldehyde or formic acid toxic products
accumulate in body tissues. This executive, with a PhD in veterinary
science, is deceiving people about very serious multiple toxicities.

Thus, there is evidence here cited from 1976 to 2004 that research and
reviews by immense vested interests about aspartame must be scrutinized with
the greatest skepticism. The greatest Internet myth about aspartame is
this: "Aspartame is the most thoroughly tested food additive in history."
************************************************** *************

A very detailed, highly credible account of the dubious approval process for
aspartame in July, 1981 is part of the just released two-hour documentary
"Sweet Misery, A Poisoned World: An Industry Case Study of a Food Supply
In Crisis" by Cori Brackett:
http://www.soundandfuryproductions.com/ 520-624-9710
2301 East Broadway, Suite 111 Tucson, AZ 85719

http://groups.yahoo.com/group/aspartameNM/message/927
Donald Rumsfeld, 1977 head of Searle Corp., got aspartame FDA approval:
Turner: Murray 2002.12.23 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1016
President Bush & formaldehyde (aspartame) toxicity: Ramazzini Foundation
carcinogenicity results Dec 2002: Soffritti: Murray 2003.08.03 rmforall

http://groups.yahoo.com/group/aspartameNM/message/874
re "dry drunk": Bisbort: danger to President Bush from aspartame toxicity:
Murray: 2002.02.24 2002.09.29 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1065
politicians and celebrities hooked on diet sodas (aspartame):
Murray 2004.03.24 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1101
John Edwards gives up Diet Coke: The Cult of Diet Coke, Eric Gillin:
Murray 2004.07.12 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1102
John Edwards still drinks Diet Coke (aspartame): TIME Europe July 19 issue:
Murray 2004.07.12 rmforall

http://groups.yahoo.com/group/aspartameNM/message/876
hyperthyroidism (Graves disease) in George and Barbara Bush, 1991--
aspartame toxicity? Roberts 1997: Murray 2002.10.09 rmforall

http://www.dorway.com/upipart1.txt
http://groups.yahoo.com/group/aspartameNM/message/262
aspartame expose 96K Oct 1987 Part 1/3: Gregory Gordon, UPI reporter:
Murray 2000.07.10 rmforall

http://www.dorway.com/enclosur.html
http://groups.yahoo.com/group/aspartameNM/message/53
aspartame history Part 1/4 1964-1976: Gold: Murray 1999.11.06 rmforall

http://groups.yahoo.com/group/aspartameNM/message/928
revolving door, Monsanto, FDA, EPA: NGIN: Murray 2002.12.23 rmforall

http://groups.yahoo.com/group/aspartameNM/message/841
RTM: Merisant Co., MSD Capital, Dell Computer Corp., NutraSweet Co.,
JW Childs Assc.: aspartame-neotame toxicity 2002.07.10 rmforall
************************************************** *************

http://www.eatright.org/Nutritive(1).pdf
J Am Diet Assoc. 2004 Feb; 104(2): 255-75.
Position of the American Dietetic Association: use of nutritive and
nonnutritive sweeteners. American Dietetic Association.

http://groups.yahoo.com/group/aspartameNM/message/1068
critique of aspartame review by American Dietetic Association Feb 2004,
Valerie B. Duffy & Madeleine J. Sigman-Grant: Murray 2004.05.14 rmforall

http://groups.yahoo.com/group/aspartameNM/message/1070
critique of aspartame review, French Food Safety Agency AFSSA 2002.05.07
aspartamgb.pdf (18 pages, in English), Martin Hirsch:
Murray 2004.04.13

http://groups.yahoo.com/group/aspartameNM/message/857
www.dorway.com: original documents and long reviews of flaws in
aspartame toxicity research: Murray 2002.07.31 rmforall

http://groups.yahoo.com/group/aspartameNM/message/858
Samuels: Strong: Roberts: Gold: flaws in double-blind studies re
aspartame and MSG toxicity: Murray 2002.08.01 rmforall

"Survey of aspartame studies: correlation of outcome and funding
sources," 1998, unpublished: http://www.dorway.com/peerrev.html
Walton found 166 separate published studies in the peer reviewed
medical literature, which had relevance for questions of human safety.
The 74 studies funded by industry all (100%) attested to aspartame's
safety, whereas of the 92 non-industry funded studies, 84 (91%)
identified a problem. Six of the seven non-industry funded studies
that were favorable to aspartame safety were from the FDA, which
has a public record that shows a strong pro-industry bias.
Ralph G. Walton, MD, Prof. of Clinical Psychology, Northeastern Ohio
Universities, College of Medicine, Dept. of Psychiatry, Youngstown,
OH 44501, Chairman, The Center for Behavioral Medicine,
Northside Medical Center, 500 Gypsy Lane, P.O. Box 240 Youngstown,
OH 44501 330-740-3621
http://www.neoucom.edu/DEPTS/Psychiatry/walton.htm

http://www.truthinlabeling.org/ Truth in Labeling Campaign [MSG]
Adrienne Samuels, PhD The toxicity/safety of processed
free glutamic acid (MSG): a study in suppression of information.
Accountability in Research 1999; 6: 259-310. 52-page review
P.O. Box 2532 Darien, Illinois 60561
858-481-9333
************************************************** *************

Research on dietary and environmental factors for cancers obviously has to
account for exposure in heavy users in vulnerable groups of people
to aspartame, methanol, formaldehyde, and formic acid
in multiple sources, including diet foods and drinks, dark wines and
liquors, tobacco and wood smoke, mobile homes, many personal care products,
and even release of methanol into the blood from degradation of pectins from
fruits and vegetables in the colon in some people, as well as folic acid,
which is a protective factor that expedites excretion of formaldehyde.

Rich Murray, MA Room For All

1943 Otowi Road, Santa Fe, New Mexico 87505 USA 505-501-2298
http://groups.yahoo.com/group/aspartameNM/messages
136 members, 1,122 posts in a public searchable archive also Co-Moderator

http://groups.yahoo.com/group/aspartame/messages
Aspartame Victims Support Group Edward Bryant Holman, Chief Moderator
851 members, 17,522 posts in a public, searchable archive
http://www.presidiotex.com/aspartame/

http://www.HolisticMed.com/aspartame
Aspartame Toxicity Information Center Mark D. Gold also Co-Moderator
12 East Side Drive #2-18 Concord, NH 03301 603-225-2110
http://www.holisticmed.com/aspartame.../methanol.html
"Scientific Abuse in Aspartame Research"

http://groups.yahoo.com/group/aspartameNM/message/957
safety of aspartame Part 1/2 12.4.2: EC HCPD-G SCF:
Murray 2003.01.12 rmforall EU Scientific Committee on Food, a whitewash

http://groups.yahoo.com/group/aspartameNM/message/1045
http://www.holisticmed.com/aspartame...2-response.htm
Mark Gold exhaustively critiques European Commission Scientific
Committee on Food re aspartame ( 2002.12.04 ): 59 pages, 230 references
************************************************** *************





 




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