Gaining Fat Cells

OK when we consume fat, I am pretty sure we either gain new fat cells
or expand the one ones already there. When we exercise, we can
decrease the size of the fat cells but we can't eliminate them. If we
have too many fat cells, regardless of their size, and we want to
eliminate them, I guess the only option is surgery.
Joe

Wrong. Where did you get this, from your doctor?

Joe wrote:

OK when we consume fat, I am pretty sure we either gain new fat cells
or expand the one ones already there. When we exercise, we can
decrease the size of the fat cells but we can't eliminate them. If we
have too many fat cells, regardless of their size, and we want to
eliminate them, I guess the only option is surgery.
Joe

On Mon, 20 Oct 2003 13:31:37 -0700, Joe joseph@here wrote:

OK when we consume fat, I am pretty sure we either gain new fat cells
or expand the one ones already there. When we exercise, we can
decrease the size of the fat cells but we can't eliminate them. If we
have too many fat cells, regardless of their size, and we want to
eliminate them, I guess the only option is surgery.
Joe

For short term fat gain, the fat cells take in more triglyceride and
get bigger. When they can't hold anymore, they send out signals that
cause the body to make more fat cells. (contrary to what use to be
believed) It is also thought that if one loses weight and maintains it
for a period if time, the body instructs unneeded fat cells to commit
suicide. One theory on what causes type 2 diabetes is a defect in the
body's ability to make new fat cells and therefore excess nutrients
have no place to go.

In any case, it's not how many fat cells you have that determine how
fat you are but how much fat they hold.

--
Ron Ritzman
http://www.panix.com/~ritzlart
Smart people can figure out my email address

Can you point me toward more information about fat cells number decreasing.
I thought I was stuck with the same number of fat cells forever.
--
SuzyQ
Weight 124
WW Lifetime Membership Feb 03

"Ron Ritzman" wrote in message
...
On Mon, 20 Oct 2003 13:31:37 -0700, Joe joseph@here wrote:

OK when we consume fat, I am pretty sure we either gain new fat cells
or expand the one ones already there. When we exercise, we can
decrease the size of the fat cells but we can't eliminate them. If we
have too many fat cells, regardless of their size, and we want to
eliminate them, I guess the only option is surgery.
Joe

For short term fat gain, the fat cells take in more triglyceride and
get bigger. When they can't hold anymore, they send out signals that
cause the body to make more fat cells. (contrary to what use to be
believed) It is also thought that if one loses weight and maintains it
for a period if time, the body instructs unneeded fat cells to commit
suicide. One theory on what causes type 2 diabetes is a defect in the
body's ability to make new fat cells and therefore excess nutrients
have no place to go.

In any case, it's not how many fat cells you have that determine how
fat you are but how much fat they hold.

--
Ron Ritzman
http://www.panix.com/~ritzlart
Smart people can figure out my email address

On Mon, 20 Oct 2003 22:29:18 -0400, Ron Ritzman
wrote:

On Mon, 20 Oct 2003 13:31:37 -0700, Joe joseph@here wrote:

OK when we consume fat, I am pretty sure we either gain new fat cells
or expand the one ones already there. When we exercise, we can
decrease the size of the fat cells but we can't eliminate them. If we
have too many fat cells, regardless of their size, and we want to
eliminate them, I guess the only option is surgery.
Joe

For short term fat gain, the fat cells take in more triglyceride and
get bigger. When they can't hold anymore, they send out signals that
cause the body to make more fat cells. (contrary to what use to be
believed) It is also thought that if one loses weight and maintains it
for a period if time, the body instructs unneeded fat cells to commit
suicide.

Where did you get THAT information please? Please cite supporting
evidence.

Joe


One theory on what causes type 2 diabetes is a defect in the
body's ability to make new fat cells and therefore excess nutrients
have no place to go.

In any case, it's not how many fat cells you have that determine how
fat you are but how much fat they hold.

"Ron Ritzman" wrote in message
...
On Mon, 20 Oct 2003 13:31:37 -0700, Joe joseph@here wrote:

OK when we consume fat, I am pretty sure we either gain new fat cells
or expand the one ones already there. When we exercise, we can
decrease the size of the fat cells but we can't eliminate them. If we
have too many fat cells, regardless of their size, and we want to
eliminate them, I guess the only option is surgery.
Joe

For short term fat gain, the fat cells take in more triglyceride and
get bigger. When they can't hold anymore, they send out signals that
cause the body to make more fat cells. (contrary to what use to be
believed) It is also thought that if one loses weight and maintains it
for a period if time, the body instructs unneeded fat cells to commit
suicide. One theory on what causes type 2 diabetes is a defect in the
body's ability to make new fat cells and therefore excess nutrients
have no place to go.

In any case, it's not how many fat cells you have that determine how
fat you are but how much fat they hold.

--
Ron Ritzman
http://www.panix.com/~ritzlart
Smart people can figure out my email address

Isn't it also true that the shrunken fat cells work hard to be filled up
again? Maybe that's why they do it, to avoid the eventual hari-kari?

Jenn

On Tue, 21 Oct 2003 11:21:45 -0700, Joe joseph@here wrote:

Where did you get THAT information please? Please cite supporting
evidence.

Get a book on biology.

Eating fat, per se, doesn't make you gain fat cells. Eating a diet
where your intake exceeds energy expenditure will cause you to gain
weight regardless of the composition of the diet.

Up to a certain point when you gain weight your fat cells expand, and
then new fat cells form. When you lose weight, fat cells deplete, and
eventually some of them die (this is called apoptosis).

Here's the introduction to a review article, note the last sentence:

"THE ADIPOCYTE IS a remarkable cell type in several respects. It
stores excess energy in the form of lipids and is thus able to
dramatically change its size in accordance with changing metabolic
needs. This ability gives adipose tissue an almost unlimited capacity
for growth, making it perhaps the only tissue in the body with the
ability to so drastically increase its size without an underlying
transformed cellular phenotype. Adipose tissue is responsive to both
central and peripheral metabolic signals and is itself capable of
secreting a number of proteins. These adipocyte-specific or enriched
proteins, termed adipokines, have been shown to have a variety of
local, peripheral, and central effects that will be discussed below.
Adipose tissue is therefore able to integrate signals from other
organs and respond by regulating secretion of multiple proteins. As an
active participant in whole body energy homeostasis, adipose tissue
can negatively influence other systems when dysregulated. Although
adipocytes are capable of increasing in size, the cellular homeostasis
and the secretory profile of larger adipocytes becomes altered and
increasingly dysregulated compared with adipocytes of smaller size.
Although the total number of adipocytes is increased with increasing
fat mass, the increased number and percentage of these large
adipocytes may partially account for the inability of adipose tissue
to function properly and contribute to some of the problems associated
with obesity."

Minireview: The adipocyte--at the crossroads of energy homeostasis,
inflammation, and atherosclerosis. Rajala MW, Scherer PE.
Endocrinology. 2003 Sep;144(9):3765-73.

Phil Scherer is a leading authority on the role of adipocytes in
energy regulation and inflammation.

FWIW,


Barbara Hirsch, Publisher
OBESITY MEDS AND RESEARCH NEWS
The latest in obesity research and weight loss drug development
http://www.obesity-news.com/

Fat cells are hard to get rid of. "If you don't eat for a couple of
days, the size of the fat cells decrease -- they lose fat. But the
number of fat cells themselves are very difficult to reduce."
biochemist Daniel Lane, of the Johns Hopkins School of Medicine
http://www.applesforhealth.com/Healt...lfatgrow4.html

Ron Ritzman wrote in message . ..
On Mon, 20 Oct 2003 13:31:37 -0700, Joe joseph@here wrote:

OK when we consume fat, I am pretty sure we either gain new fat cells
or expand the one ones already there. When we exercise, we can
decrease the size of the fat cells but we can't eliminate them. If we
have too many fat cells, regardless of their size, and we want to
eliminate them, I guess the only option is surgery.
Joe

For short term fat gain, the fat cells take in more triglyceride and
get bigger. When they can't hold anymore, they send out signals that
cause the body to make more fat cells. (contrary to what use to be
believed) It is also thought that if one loses weight and maintains it
for a period if time, the body instructs unneeded fat cells to commit
suicide. One theory on what causes type 2 diabetes is a defect in the
body's ability to make new fat cells and therefore excess nutrients
have no place to go.

In any case, it's not how many fat cells you have that determine how
fat you are but how much fat they hold.