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#1
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Another Egg Study
Title: Eggs modulate the inflammatory response to carbohydrate restricted
diets in overweight men http://www.nutritionandmetabolism.com/content/5/1/6 Background Carbohydrate restricted diets (CRD) consistently lower glucose and insulin levels and improve atherogenic dyslipidemia [decreasing triglycerides and increasing HDL cholesterol (HDL-C)]. We have previously shown that male subjects following a CRD experienced significant increases in HDL-C only if they were consuming a higher intake of cholesterol provided by eggs compared to those individuals who were taking lower concentrations of dietary cholesterol. Here, as a follow up of our previous study, we examined the effects of eggs (a source of both dietary cholesterol and lutein) on adiponectin, a marker of insulin sensitivity, and on inflammatory markers in the context of a CRD. Methods Twenty eight overweight men [body mass index (BMI) 26-37 kg/m2] aged 40-70 y consumed an ad libitum CRD (% energy from CHO:fatrotein = 17:57:26) for 12 wk. Subjects were matched by age and BMI and randomly assigned to consume eggs (EGG, n=15) (640 mg additional cholesterol/day provided by eggs) or placebo (SUB, n=13) (no additional dietary cholesterol). Fasting blood samples were drawn before and after the intervention to assess plasma lipids, insulin, adiponectin and markers of inflammation including C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-I+/-), interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1(VCAM-1). Results Body weight, percent total body fat and trunk fat were reduced for all subjects after 12 wk (P 0.0001). Increases in adiponectin were also observed (P 0.01). Subjects in the EGG group had a 21% increase in this adipokine compared to a 7% increase in the SUB group (P 0.05). Plasma CRP was significantly decreased only in the EGG group (P 0.05). MCP-1 levels were decreased for the SUB group (P 0.001), but unchanged in the EGG group. VCAM-1, ICAM-1, TNF-alpha and IL-8 were not modified by CRD or eggs. Conclusions A CRD with daily intake of eggs decreased plasma CRP and increased plasma adiponectin compared to a CRD without eggs. These findings indicate that eggs make a significant contribution to the anti-inflammatory effects of CRD, possibly due to the presence of cholesterol, which increases HDL-C and to the antioxidant lutein which modulates certain inflammatory responses. |
#2
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Another Egg Study
On Feb 21, 4:54 am, "Roger Zoul" wrote:
Title: Eggs modulate the inflammatory response to carbohydrate restricted diets in overweight men http://www.nutritionandmetabolism.com/content/5/1/6 Background We have previously shown that male subjects following a CRD experienced significant increases in HDL-C only if they were consuming a higher intake of cholesterol provided by eggs compared to those individuals who were taking lower concentrations of dietary cholesterol. I did not know that. Methods Subjects were matched by age and BMI and randomly assigned to consume eggs (EGG, n=15) (640 mg additional cholesterol/day provided by eggs) or placebo (SUB, n=13) (no additional dietary cholesterol). Any ideas on what a placebo egg is? Maybe smart beaters or whatever they call those cholesterol free egg substitutes? Thanks for the link Rog. I'm gonna go have some eggs in about an hour or so. |
#3
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Another Egg Study
"Roger Zoul" writes:
Title: Eggs modulate the inflammatory response to carbohydrate restricted diets in overweight men I just had five eggs this morning. Yay! Farm-fresh, local eggs too; less than a week old. Yum. Not exactly pasture-raised--there's not much pasture in Illinois in February--but the yolks are still a much deeper orange than store-bought eggs, showing the chickens are finding more than grain to eat. -- Aaron -- 285/253/200 -- aaron.baugher.biz |
#4
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Another Egg Study
Hollywood wrote:
"Roger Zoul" wrote: Title: Eggs modulate the inflammatory response to carbohydrate restricted diets in overweight men http://www.nutritionandmetabolism.com/content/5/1/6 Background We have previously shown that male subjects following a CRD experienced significant increases in HDL-C only if they were consuming a higher intake of cholesterol provided by eggs compared to those individuals who were taking lower concentrations of dietary cholesterol. I did not know that. But is it necessarily the dietary cholesterol in the eggs that matters? Methods Subjects were matched by age and BMI and randomly assigned to consume eggs (EGG, n=15) (640 mg additional cholesterol/day provided by eggs) or placebo (SUB, n=13) (no additional dietary cholesterol). Any ideas on what a placebo egg is? Maybe smart beaters or whatever they call those cholesterol free egg substitutes? In particular I'm interested in the amino acid balance and fat content of the substitute. Eggs were called "Eggs, Nature's most nearly perfect food" for a while because they had the best known amino acid balance of any food that had been measured at the time. What if this effect is from fixing a previously unknown amino acid deficiency? What if it's from one of the types of fatty acid in the yolk? There are other factors in an egg than cholesterol. |
#5
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Another Egg Study
"Roger Zoul" wrote in message ... Title: Eggs modulate the inflammatory response to carbohydrate restricted diets in overweight men http://www.nutritionandmetabolism.com/content/5/1/6 Background Carbohydrate restricted diets (CRD) consistently lower glucose and insulin levels and improve atherogenic dyslipidemia [decreasing triglycerides and increasing HDL cholesterol (HDL-C)]. We have previously shown that male subjects following a CRD experienced significant increases in HDL-C only if they were consuming a higher intake of cholesterol provided by eggs compared to those individuals who were taking lower concentrations of dietary cholesterol. Here, as a follow up of our previous study, we examined the effects of eggs (a source of both dietary cholesterol and lutein) on adiponectin, a marker of insulin sensitivity, and on inflammatory markers in the context of a CRD. Methods Twenty eight overweight men [body mass index (BMI) 26-37 kg/m2] aged 40-70 y consumed an ad libitum CRD (% energy from CHO:fatrotein = 17:57:26) for 12 wk. Subjects were matched by age and BMI and randomly assigned to consume eggs (EGG, n=15) (640 mg additional cholesterol/day provided by eggs) or placebo (SUB, n=13) (no additional dietary cholesterol). Fasting blood samples were drawn before and after the intervention to assess plasma lipids, insulin, adiponectin and markers of inflammation including C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-I+/-), interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1(VCAM-1). Results Body weight, percent total body fat and trunk fat were reduced for all subjects after 12 wk (P 0.0001). Increases in adiponectin were also observed (P 0.01). Subjects in the EGG group had a 21% increase in this adipokine compared to a 7% increase in the SUB group (P 0.05). Plasma CRP was significantly decreased only in the EGG group (P 0.05). MCP-1 levels were decreased for the SUB group (P 0.001), but unchanged in the EGG group. VCAM-1, ICAM-1, TNF-alpha and IL-8 were not modified by CRD or eggs. Conclusions A CRD with daily intake of eggs decreased plasma CRP and increased plasma adiponectin compared to a CRD without eggs. These findings indicate that eggs make a significant contribution to the anti-inflammatory effects of CRD, possibly due to the presence of cholesterol, which increases HDL-C and to the antioxidant lutein which modulates certain inflammatory responses. Thanks for the post. While most of the biochemistry here goes over my head, I think it is probably improper to conclude that cholesterol is the key. Eggs have lots of stuff in them. They may be right, of course. It is too bad they do not say how many eggs the subjects got per day. Wouldn't it be wild if the supplement stores started selling cholesterol pills to prevent inflammation and thus heart disease! |
#6
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Another Egg Study
On Feb 21, 12:22 pm, "Cubit" wrote:
It is too bad they do not say how many eggs the subjects got per day. I backed it out. 640 mg cholesterol works out to about 3 large - extra large eggs. |
#7
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Another Egg Study
"Hollywood" wrote in message ... On Feb 21, 12:22 pm, "Cubit" wrote: It is too bad they do not say how many eggs the subjects got per day. I backed it out. 640 mg cholesterol works out to about 3 large - extra large eggs. Thank you. I just checked Fitday. If dietary cholesterol is good, I'm in great shape. My blood tests check a lot of things, but they don't seem to check for inflammation, yet. |
#8
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Another Egg Study
Roger Zoul wrote: Title: Eggs modulate the inflammatory response to carbohydrate restricted diets in overweight men What is this "inflammatory response"? I haven't experienced it as I can think of, nor did I really read any "overweight man" switching to Atkins claiming that he was struck by an inflammation. I would be glad to know what it is. -- Newsoffice.de - Die Onlinesoftware zum Lesen und Schreiben im Usenet Die Signatur läßt sich nach Belieben anpassen ;-) |
#9
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Another Egg Study
On Sat, 23 Feb 2008 15:51:34 -0500, Hakan Lane wrote:
Roger Zoul wrote: Title: Eggs modulate the inflammatory response to carbohydrate restricted diets in overweight men What is this "inflammatory response"? I haven't experienced it as I can think of, nor did I really read any "overweight man" switching to Atkins claiming that he was struck by an inflammation. I would be glad to know what it is. I think it's a scam and something used to sell studies. -- Using Opera's revolutionary e-mail client: http://www.opera.com/mail/ |
#10
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Another Egg Study
Bob wrote:
Hakan Lane wrote: Roger Zoul wrote: Title: Eggs modulate the inflammatory response to carbohydrate * restricted diets in overweight men *What is this "inflammatory response"? I haven't experienced it as I can * think of, nor did I really read any "overweight man" switching to Atkins * claiming that he was struck by an inflammation. I would be glad to know * what it is. I wondered that as well. Very many people have reported reduced swelling and that's a "response" toward the good. Not everyone reports such, but many do. I think it's a scam and something used to sell studies. Propaganda to get funding. Chuckle. |
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