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Exposure to Chemical Pollutants Increases Fat



 
 
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  #1  
Old July 9th, 2011, 04:18 AM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
jay[_2_]
external usenet poster
 
Posts: 68
Default Exposure to Chemical Pollutants Increases Fat

http://www.scientificamerican.com/ar...tants-fat-diet

Study Finds Exposure to Chemical Pollutants Increases Fat
Rats exposed to high levels of chemical pollutants in fish oil could
not regulate fat properly
By Sara Goodman | January 15, 2010 | 8

FAT CHEMICAL: A chemical found in fatty foods could be sentencing
people to metabolic problems such as obesity and fatigue.

Researchers have for the first time found a connection between
exposure to certain chemicals and insulin resistance, according to a
study published in the online edition of Environmental Health
Perspectives.

A group of European scientists examined whether exposure to persistent
organic pollutants (POPs) contributed to insulin resistance, which has
been increasing around the world. More than 25 percent of U.S. adults
suffer from metabolic conditions stemming from insulin resistance that
include fatigue, obesity and difficulty regulating blood levels of fat
and sugar.

Researchers fed rats a high-fat diet of either crude or refined fish
oil from farmed Atlantic salmon over 28 days. The crude fish oil
contained average levels of POPs that people are exposed to through
fish consumption, while the refined oil contained none. Both had equal
fat levels.

They found that rats exposed to the crude fish oil developed belly fat
and could not regulate fat properly. They had higher levels of
cholesterol and several fatty acids in their livers. Those exposed to
the refined fish oil experienced none of those symptoms.

Researchers said the findings provide "compelling evidence" of a
causal relationship between POP exposure common in the food chain and
insulin resistance, and highlight the need to understand the
interactions of POPs and fat-containing foods such as fish, dairy
products and meat.

How to deal with POPs is particularly challenging because they persist
in the environment for long periods and can build up in animals'
tissues.

The 2001 Stockholm Convention, which the United States has ratified
but not signed, lists and bans numerous POPs from manufacture and use.
The researchers say their evidence reinforces the need to have
international agreements aimed at limiting the release of POPs into
the environment in an effort to protect public health.
  #2  
Old July 9th, 2011, 11:08 PM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
montygraham
external usenet poster
 
Posts: 1
Default Exposure to Chemical Pollutants Increases Fat

Another instance where they should have had two other groups of rats,
both of which would be fed coconut oil rather than fish oil, one would
get the POPs and one would not. My guess is that they are not
familiar with the relevant literature, because it suggests that
coconut oil and POPs might not present any major problem, unlike fish
oil and POPs. If so, it would have been yet another good
demonstration of the apparent dangers of fish oil.
  #3  
Old July 10th, 2011, 01:08 AM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
jay[_2_]
external usenet poster
 
Posts: 68
Default Exposure to Chemical Pollutants Increases Fat

On Jul 9, 5:08*pm, montygraham wrote:
Another instance where they should have had two other groups of rats,
both of which would be fed coconut oil rather than fish oil, one would
get the POPs and one would not. *My guess is that they are not
familiar with the relevant literature, because it suggests that
coconut oil and POPs might not present any major problem, unlike fish
oil and POPs. *If so, it would have been yet another good
demonstration of the apparent dangers of fish oil.


Some POPs alter cells via a non-ROS mechanism. Some POPs produce
reactive quinones that bind DNA. POPs tend to hyperactive Phase I
enzymes which tend to produce more reactive chemicals so that they can
by bound and excreted by Phase II enzymes/anti-oxidants. Reducing
excess iron, proteins in addition to polyunsaturated oils should help
also.
  #4  
Old July 10th, 2011, 04:04 AM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
jay[_2_]
external usenet poster
 
Posts: 68
Default Exposure to Chemical Pollutants Increases Fat

Study Finds Exposure to Chemical Pollutants Increases Fat
Rats exposed to high levels of chemical pollutants in fish oil could
not regulate fat properly


Apparently, the short-term & instant pleasure of eating processed
foods concocted in the Labs of Frito-Lay outweighs long-term concerns
for one's health or pocketbook

MISSISSIPPI MOST OBESE STATE, COLORADO LEAST
The number of obese U.S. adults rose in 16 states in the last year,
helping to push obesity rates in a dozen states above 30 percent,
according to a report released on Thursday.

By that measure, Mississippi is the fattest state in the union with an
adult obesity rate of 34.4 percent. Colorado is the least obese --
with a rate of 19.8 percent -- and the only state with an adult
obesity rate below 20 percent, according to "F as in Fat," an annual
report from the Trust for America's Health and the Robert Wood Johnson
Foundation.

While the number of states showing significant year-over-year
increases in obesity has been slowing, no state chalked up an actual
decline. Even Colorado does not win high marks -- its score means one
in five state residents is at higher risk for conditions like heart
disease and diabetes.

"Today, the state with the lowest adult obesity rate would have had
the highest rate in 1995," said Jeff Levi, executive director of the
Trust for America's Health.

Four years ago, only one U.S. state had an adult obesity rate above 30
percent, according to the report, which defines adult obesity as a
having a body mass index -- a weight-to-height ratio -- of 30 or more.

Over the last two decades, people in the United States have been
eating less nutritious food and more of it. At the same time, activity
levels have fallen, Levi said.

"If we're going to reverse the obesity trends, willpower alone won't
do it. We're going to have to make healthier choices easier for
Americans," Levi said.

Public health experts around the world have raised the alarm about
exploding rates of obesity -- particularly among children -- and many
are promoting efforts to encourage exercise and easier access to
affordable, healthy food.

In the United States -- where two-thirds of adults and nearly one-
third of children are obese or overweight -- the obesity epidemic is
sending healthcare costs higher and threatening everything from worker
productivity to military recruitment.

Some groups say such behavioral initiatives are not enough, arguing
that food manufacturers and restaurant chains need limits on how they
market to children.

The Center for Science in the Public Interest, a U.S. consumer group,
last year sued McDonald's Corp to stop the world's largest hamburger
chain from using Happy Meal toys to lure children into its
restaurants. Last month, the American Academy of Pediatrics -- a group
of U.S. pediatricians -- called for a ban on junk food ads aimed at
children.

The food industry -- which has significantly increased portion sizes
in restaurants and packaged foods like sugar-sweetened beverages over
the last 20 years -- is fighting regulation efforts and has adopted
the mantra of "personal responsibility."

To that end, food and beverage companies say consumers have the right
to choose what they eat and should balance their caloric intake with
activity.

The report released on Thursday showed that over the past 15 years,
seven states have doubled their rate of obesity and 10 states have
doubled their rate of diabetes.

Since 1995, obesity rates have risen fastest in Oklahoma, Alabama and
Tennessee, while Colorado, Connecticut and Washington, D.C., had the
slowest increases.

Adults from racial and ethnic minority groups, as well as those with
less education and lower incomes, continue to have the highest overall
obesity rates.

http://www.reuters.com/article/2011/...7663JD20110707
  #5  
Old July 10th, 2011, 06:34 PM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
Billy[_4_]
external usenet poster
 
Posts: 215
Default Exposure to Chemical Pollutants Increases Fat

In article
,
jay wrote:

http://www.reuters.com/article/2011/...7663JD20110707


The report released on Thursday showed that over the past 15 years,
seven states have doubled their rate of obesity and 10 states have
doubled their rate of diabetes.

Since 1995, obesity rates have risen fastest in Oklahoma, Alabama and
Tennessee, while Colorado, Connecticut and Washington, D.C., had the
slowest increases.

Adults from racial and ethnic minority groups, as well as those with
less education and lower incomes, continue to have the highest overall
obesity rates.


I just wanted to point out to the potential big-ots out there that in
2005 12.5% of Hispanics, and 25.8% of black People were poor.

http://washingtonexaminer.com/news/2...gains-reversed
-great-recession
Economists say the Great Recession lasted from 2007 to 2009. In 2004,
the median net worth of white households was $134,280, compared with
$13,450 for black households, according to an analysis of Federal
Reserve data by the Economic Policy Institute. By 2009, the median net
worth for white households had fallen 24 percent to $97,860; the median
black net worth had fallen 83 percent to $2,170, according to the EPI.
Algernon Austin, director of the EPI's Program on Race, Ethnicity and
the Economy, described the current wealth gap this way: "In 2009, for
every dollar of wealth the average white household had, black households
only had two cents."

Since the end of the recession, the overall unemployment rate has fallen
from 9.4 to 9.1 percent, while the black unemployment rate has risen
from 14.7 to 16.2 percent, according to the Department of Labor.
----

Racism in America not only affects people financially, but it also makes
them sick, because the most calories for the buck comes from nutrient
poor "processed foods". The most reliable predictor of obesity in
America today is a personšs wealth.
http://www.nytimes.com/2007/04/22/magazine/22wwlnlede.t.html
--
- Billy

Mad dog Republicans to the right. Democratic spider webs to the left. True conservatives, and liberals not to be found anywhere in the phantasmagoria
of the American political landscape.

America is not broke. The country is awash in wealth and cash.
It's just that it's not in your hands. It has been transferred, in the
greatest heist in history, from the workers and consumers to the banks
and the portfolios of the uber-rich.
http://www.politifact.com/wisconsin/.../michael-moore
/michael-moore-says-400-americans-have-more-wealth-/
  #6  
Old July 10th, 2011, 06:52 PM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
Billy[_4_]
external usenet poster
 
Posts: 215
Default Exposure to Chemical Pollutants Increases Fat

In article
,
montygraham wrote:

Another instance where they should have had two other groups of rats,
both of which would be fed coconut oil rather than fish oil, one would
get the POPs and one would not. My guess is that they are not
familiar with the relevant literature, because it suggests that
coconut oil and POPs might not present any major problem, unlike fish
oil and POPs. If so, it would have been yet another good
demonstration of the apparent dangers of fish oil.


http://www.scientificamerican.com/ar...nsulin-resista
nce-organic-pollutants-fat-diet
"Researchers fed rats a high-fat diet of either crude or refined fish
oil from farmed Atlantic salmon over 28 days.

The crude fish oil contained average levels of POPs that people are
exposed to through fish consumption,

while the refined oil contained none.

Both had equal fat levels."
---

You can buy "organic" fish oil that will be free of "persistent organic
pollutants".

Why introduce "might not" and maybe, into a discussion of the results
where it has no bearing? The point is:

rats exposed to the crude fish oil (POPs) developed belly fat and could
not regulate fat properly. They had higher levels of cholesterol and
several fatty acids in their livers.

Those (rats) exposed to the refined fish oil (no POPs) experienced none
of those symptoms.
--
- Billy

Mad dog Republicans to the right. Democratic spider webs to the left. True conservatives, and liberals not to be found anywhere in the phantasmagoria
of the American political landscape.

America is not broke. The country is awash in wealth and cash.
It's just that it's not in your hands. It has been transferred, in the
greatest heist in history, from the workers and consumers to the banks
and the portfolios of the uber-rich.
http://www.politifact.com/wisconsin/.../michael-moore
/michael-moore-says-400-americans-have-more-wealth-/
  #7  
Old July 10th, 2011, 06:53 PM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
Billy[_4_]
external usenet poster
 
Posts: 215
Default Exposure to Chemical Pollutants Increases Fat

In article
,
jay wrote:

On Jul 9, 5:08*pm, montygraham wrote:
Another instance where they should have had two other groups of rats,
both of which would be fed coconut oil rather than fish oil, one would
get the POPs and one would not. *My guess is that they are not
familiar with the relevant literature, because it suggests that
coconut oil and POPs might not present any major problem, unlike fish
oil and POPs. *If so, it would have been yet another good
demonstration of the apparent dangers of fish oil.


Some POPs alter cells via a non-ROS mechanism. Some POPs produce
reactive quinones that bind DNA. POPs tend to hyperactive Phase I
enzymes which tend to produce more reactive chemicals so that they can
by bound and excreted by Phase II enzymes/anti-oxidants. Reducing
excess iron, proteins in addition to polyunsaturated oils should help
also.


Do you have a citation for the above?
--
- Billy

Mad dog Republicans to the right. Democratic spider webs to the left. True conservatives, and liberals not to be found anywhere in the phantasmagoria
of the American political landscape.

America is not broke. The country is awash in wealth and cash.
It's just that it's not in your hands. It has been transferred, in the
greatest heist in history, from the workers and consumers to the banks
and the portfolios of the uber-rich.
http://www.politifact.com/wisconsin/.../michael-moore
/michael-moore-says-400-americans-have-more-wealth-/
  #8  
Old July 10th, 2011, 09:51 PM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
[email protected] |
external usenet poster
 
Posts: 39
Default Exposure to Chemical Pollutants Increases Fat

On Jul 9, 8:04*pm, jay wrote:
Study Finds Exposure to Chemical Pollutants Increases Fat
Rats exposed to high levels of chemical pollutants in fish oil could
not regulate fat properly


Apparently, the short-term & instant pleasure of eating processed
foods concocted in the Labs of Frito-Lay outweighs long-term concerns
for one's health or pocketbook

MISSISSIPPI MOST OBESE STATE, COLORADO LEAST
The number of obese U.S. adults rose in 16 states in the last year,
helping to push obesity rates in a dozen states above 30 percent,
according to a report released on Thursday.

By that measure, Mississippi is the fattest state in the union with an
adult obesity rate of 34.4 percent. Colorado is the least obese --
with a rate of 19.8 percent -- and the only state with an adult
obesity rate below 20 percent, according to "F as in Fat," an annual
report from the Trust for America's Health and the Robert Wood Johnson
Foundation.

While the number of states showing significant year-over-year
increases in obesity has been slowing, no state chalked up an actual
decline. Even Colorado does not win high marks -- its score means one
in five state residents is at higher risk for conditions like heart
disease and diabetes.

"Today, the state with the lowest adult obesity rate would have had
the highest rate in 1995," said Jeff Levi, executive director of the
Trust for America's Health.

Four years ago, only one U.S. state had an adult obesity rate above 30
percent, according to the report, which defines adult obesity as a
having a body mass index -- a weight-to-height ratio -- of 30 or more.

Over the last two decades, people in the United States have been
eating less nutritious food and more of it. At the same time, activity
levels have fallen, Levi said.

"If we're going to reverse the obesity trends, willpower alone won't
do it. We're going to have to make healthier choices easier for
Americans," Levi said.

Public health experts around the world have raised the alarm about
exploding rates of obesity -- particularly among children -- and many
are promoting efforts to encourage exercise and easier access to
affordable, healthy food.

In the United States -- where two-thirds of adults and nearly one-
third of children are obese or overweight -- the obesity epidemic is
sending healthcare costs higher and threatening everything from worker
productivity to military recruitment.

Some groups say such behavioral initiatives are not enough, arguing
that food manufacturers and restaurant chains need limits on how they
market to children.

The Center for Science in the Public Interest, a U.S. consumer group,
last year sued McDonald's Corp to stop the world's largest hamburger
chain from using Happy Meal toys to lure children into its
restaurants. Last month, the American Academy of Pediatrics -- a group
of U.S. pediatricians -- called for a ban on junk food ads aimed at
children.

The food industry -- which has significantly increased portion sizes
in restaurants and packaged foods like sugar-sweetened beverages over
the last 20 years -- is fighting regulation efforts and has adopted
the mantra of "personal responsibility."

To that end, food and beverage companies say consumers have the right
to choose what they eat and should balance their caloric intake with
activity.

The report released on Thursday showed that over the past 15 years,
seven states have doubled their rate of obesity and 10 states have
doubled their rate of diabetes.

Since 1995, obesity rates have risen fastest in Oklahoma, Alabama and
Tennessee, while Colorado, Connecticut and Washington, D.C., had the
slowest increases.

Adults from racial and ethnic minority groups, as well as those with
less education and lower incomes, continue to have the highest overall
obesity rates.

http://www.reuters.com/article/2011/...7663JD20110707


The CSPI is part of the problem and no better of a solution
than McDs.
  #9  
Old July 10th, 2011, 11:04 PM posted to alt.support.diet.low-carb
Billy[_4_]
external usenet poster
 
Posts: 215
Default Exposure to Chemical Pollutants Increases Fat

In article
,
|" wrote:

On Jul 9, 8:04*pm, jay wrote:
Study Finds Exposure to Chemical Pollutants Increases Fat
Rats exposed to high levels of chemical pollutants in fish oil could
not regulate fat properly


Apparently, the short-term & instant pleasure of eating processed
foods concocted in the Labs of Frito-Lay outweighs long-term concerns
for one's health or pocketbook

MISSISSIPPI MOST OBESE STATE, COLORADO LEAST
The number of obese U.S. adults rose in 16 states in the last year,
helping to push obesity rates in a dozen states above 30 percent,
according to a report released on Thursday.

By that measure, Mississippi is the fattest state in the union with an
adult obesity rate of 34.4 percent. Colorado is the least obese --
with a rate of 19.8 percent -- and the only state with an adult
obesity rate below 20 percent, according to "F as in Fat," an annual
report from the Trust for America's Health and the Robert Wood Johnson
Foundation.

While the number of states showing significant year-over-year
increases in obesity has been slowing, no state chalked up an actual
decline. Even Colorado does not win high marks -- its score means one
in five state residents is at higher risk for conditions like heart
disease and diabetes.

"Today, the state with the lowest adult obesity rate would have had
the highest rate in 1995," said Jeff Levi, executive director of the
Trust for America's Health.

Four years ago, only one U.S. state had an adult obesity rate above 30
percent, according to the report, which defines adult obesity as a
having a body mass index -- a weight-to-height ratio -- of 30 or more.

Over the last two decades, people in the United States have been
eating less nutritious food and more of it. At the same time, activity
levels have fallen, Levi said.

"If we're going to reverse the obesity trends, willpower alone won't
do it. We're going to have to make healthier choices easier for
Americans," Levi said.

Public health experts around the world have raised the alarm about
exploding rates of obesity -- particularly among children -- and many
are promoting efforts to encourage exercise and easier access to
affordable, healthy food.

In the United States -- where two-thirds of adults and nearly one-
third of children are obese or overweight -- the obesity epidemic is
sending healthcare costs higher and threatening everything from worker
productivity to military recruitment.

Some groups say such behavioral initiatives are not enough, arguing
that food manufacturers and restaurant chains need limits on how they
market to children.

The Center for Science in the Public Interest, a U.S. consumer group,
last year sued McDonald's Corp to stop the world's largest hamburger
chain from using Happy Meal toys to lure children into its
restaurants. Last month, the American Academy of Pediatrics -- a group
of U.S. pediatricians -- called for a ban on junk food ads aimed at
children.

The food industry -- which has significantly increased portion sizes
in restaurants and packaged foods like sugar-sweetened beverages over
the last 20 years -- is fighting regulation efforts and has adopted
the mantra of "personal responsibility."

To that end, food and beverage companies say consumers have the right
to choose what they eat and should balance their caloric intake with
activity.

The report released on Thursday showed that over the past 15 years,
seven states have doubled their rate of obesity and 10 states have
doubled their rate of diabetes.

Since 1995, obesity rates have risen fastest in Oklahoma, Alabama and
Tennessee, while Colorado, Connecticut and Washington, D.C., had the
slowest increases.

Adults from racial and ethnic minority groups, as well as those with
less education and lower incomes, continue to have the highest overall
obesity rates.

http://www.reuters.com/article/2011/...7663JD20110707


The CSPI is part of the problem and no better of a solution
than McDs.


Do you have any facts, or is this just your opinion?
--
- Billy

Mad dog Republicans to the right. Democratic spider webs to the left. True conservatives, and liberals not to be found anywhere in the phantasmagoria
of the American political landscape.

America is not broke. The country is awash in wealth and cash.
It's just that it's not in your hands. It has been transferred, in the
greatest heist in history, from the workers and consumers to the banks
and the portfolios of the uber-rich.
http://www.politifact.com/wisconsin/.../michael-moore
/michael-moore-says-400-americans-have-more-wealth-/
  #10  
Old July 11th, 2011, 04:12 AM posted to sci.med.nutrition,alt.support.diabetes,alt.support.diet.low-carb
jay[_2_]
external usenet poster
 
Posts: 68
Default Exposure to Chemical Pollutants Increases Fat

... citation for the above?

Receptor- and reactive intermediate-mediated mechanisms of
teratogenesis.
Drugs and environmental chemicals can adversely alter the development
of the fetus at critical periods during pregnancy, resulting in death,
or in structural and functional birth defects in the surviving
offspring. This process of teratogenesis may not be evident until a
decade or more after birth. Postnatal functional abnormalities include
deficits in brain function, a variety of metabolic diseases, and
cancer. Due to the high degree of fetal cellular division and
differentiation, and to differences from the adult in many biochemical
pathways, the fetus is highly susceptible to teratogens, typically at
low exposure levels that do not harm the mother. Insights into the
mechanisms of teratogenesis come primarily from animal models and in
vitro systems, and involve either receptor-mediated or reactive
intermediate-mediated processes. Receptor-mediated mechanisms
involving the reversible binding of xenobiotic substrates to a
specific receptor are exemplified herein by the interaction of the
environmental chemical 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD or
"dioxin") with the cytosolic aryl hydrocarbon receptor (AHR), which
translocates to the nucleus and, in association with other proteins,
binds to AH-responsive elements (AHREs) in numerous genes, initiating
changes in gene transcription that can perturb development.
Alternatively, many xenobiotics are bioactivated by fetal enzymes like
the cytochromes P450 (CYPs) and prostaglandin H synthases (PHSs) to
highly unstable electrophilic or free radical reactive intermediates.
Electrophilic reactive intermediates can covalently (irreversibly)
bind to and alter the function of essential cellular macromolecules
(proteins, DNA), causing developmental anomalies. Free radical
reactive intermediates can enhance the formation of reactive oxygen
species (ROS), resulting in oxidative damage to cellular
macromolecules and/or altered signal transduction. The teratogenicity
of reactive intermediates is determined to a large extent by the
balance among embryonic and fetal pathways of xenobiotic
bioactivation, detoxification of the xenobiotic reactive intermediate,
detoxification of ROS, and repair of oxidative macromolecular damage.
PMID: 20020262
 




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