Curry and Cauliflower Could Halt Prostate Cancer...

http://ur.rutgers.edu/medrel/viewArt...ArticleID=4912

Curry and Cauliflower Could Halt Prostate Cancer

January 15, 2006

EDITOR'S NOTE: Professor Kong may be reached at 732-445-3831, ext. 226, or
e-mail . From Jan.14 through Jan. 16 only, he may be
contacted at 908-823-9251. A copy of the paper may be obtained by sending an
e-mail to .

NEW BRUNSWICK/PISCATAWAY, N.J. - Rutgers researchers have found that the
curry spice turmeric holds real potential for the treatment and prevention
of prostate cancer, particularly when combined with certain vegetables.

The scientists tested turmeric, also known as curcumin, along with phenethyl
isothiocyanate (PEITC), a naturally occurring substance particularly
abundant in a group of vegetables that includes watercress, cabbage, winter
cress, broccoli, Brussels sprouts, kale, cauliflower, kohlrabi and turnips.

"The bottom line is that PEITC and curcumin, alone or in combination,
demonstrate significant cancer-preventive qualities in laboratory mice, and
the combination of PEITC and curcumin could be effective in treating
established prostate cancers," said Ah-Ng Tony Kong, a professor of
pharmaceutics at Rutgers, The State University of New Jersey.

The discovery was announced in the Jan. 15 issue of the journal Cancer
Research by Kong and his colleagues at Rutgers' Ernest Mario School of
Pharmacy.

Prostate cancer is the second leading cause of cancer death in men in the
United States, with a half-million new cases appearing each year. The
incidence and mortality of prostate cancer have not decreased in past
decades despite tremendous efforts and resources devoted to treatment. This
is because advanced prostate cancer cells are barely responsive even to high
concentrations of chemotherapeutic agents or radiotherapy.

The authors noted that in contrast to the high incidence of prostate cancer
in the United States, the incidence of this disease is very low in India.
This has been attributed to the dietary consumption of large amounts of
plant-based foods rich in phytochemicals - nonnutritive plant chemicals that
have protective or disease-preventive properties.

Consequently, scientists have been investigating intervention options based
on compounds found in edible and medicinal plants. They have had some
success, and a majority of patients with prostate cancer are now combining
the conventional therapies with these compounds as alternative,
supplementary or complementary medications.

For Kong's study, researchers used mice bred so that their immune systems
would not reject foreign biological material and injected the mice with
cells from human prostate cancer cell lines to grow tumors against which the
compounds could be tested.

"Despite convincing data from laboratory cell cultures, we knew little about
how PEITC and curcumin would perform in live animals, especially on prostate
cancer," Kong said. "So we undertook this study to evaluate how effective
PEITC and curcumin might be - individually and in combination - to prevent
and possibly treat prostate cancer."

The researchers injected the mice with curcumin or PEITC, alone or in
combination, three times a week for four weeks, beginning a day before the
introduction of the prostate cancer cells. They found the injections
significantly retarded the growth of cancerous tumors. Using PEITC and
curcumin in tandem produced even stronger effects.

The group went on to evaluate the therapeutic potential of curcumin and
PEITC in mice with well-established tumors, and the results showed that
PEITC or curcumin alone had little effect, whereas the combination of
curcumin and PEITC significantly reduced tumor growth.

The paper, "Combined Inhibitory Effects of Curcumin and Phenethyl
Isothiocyanate on the Growth of Human PC-3 Prostate Xenografts in
Immunodeficient Mice," is available at cancerres.aacrjournals.org.

The authors are Tin Oo Khor, Young-Sam Keum, Wen Lin, Jung-Hwan Kim, Rong
Hu, Guoxiang Shen, Changjiang Xu, Avanthika Gopalakrishnan, Bandaru Reddy,
Xi Zheng, Allan H. Conney and Ah-Ng Tony Kong, all from Rutgers.

--
Ken

"Buddhism elucidates why we are sentient."
"Karma means that you don't get away with anything."

Every male in the universe should consider this study and add tumeric
and kale to their diet.



On Mon, 16 Jan 2006 07:30:42 -0600, "Ken Kubos"
wrote:

http://ur.rutgers.edu/medrel/viewArt...ArticleID=4912

Curry and Cauliflower Could Halt Prostate Cancer

January 15, 2006

EDITOR'S NOTE: Professor Kong may be reached at 732-445-3831, ext. 226, or
e-mail . From Jan.14 through Jan. 16 only, he may be
contacted at 908-823-9251. A copy of the paper may be obtained by sending an
e-mail to .

NEW BRUNSWICK/PISCATAWAY, N.J. - Rutgers researchers have found that the
curry spice turmeric holds real potential for the treatment and prevention
of prostate cancer, particularly when combined with certain vegetables.

The scientists tested turmeric, also known as curcumin, along with phenethyl
isothiocyanate (PEITC), a naturally occurring substance particularly
abundant in a group of vegetables that includes watercress, cabbage, winter
cress, broccoli, Brussels sprouts, kale, cauliflower, kohlrabi and turnips.

"The bottom line is that PEITC and curcumin, alone or in combination,
demonstrate significant cancer-preventive qualities in laboratory mice, and
the combination of PEITC and curcumin could be effective in treating
established prostate cancers," said Ah-Ng Tony Kong, a professor of
pharmaceutics at Rutgers, The State University of New Jersey.

The discovery was announced in the Jan. 15 issue of the journal Cancer
Research by Kong and his colleagues at Rutgers' Ernest Mario School of
Pharmacy.

Prostate cancer is the second leading cause of cancer death in men in the
United States, with a half-million new cases appearing each year. The
incidence and mortality of prostate cancer have not decreased in past
decades despite tremendous efforts and resources devoted to treatment. This
is because advanced prostate cancer cells are barely responsive even to high
concentrations of chemotherapeutic agents or radiotherapy.

The authors noted that in contrast to the high incidence of prostate cancer
in the United States, the incidence of this disease is very low in India.
This has been attributed to the dietary consumption of large amounts of
plant-based foods rich in phytochemicals - nonnutritive plant chemicals that
have protective or disease-preventive properties.

Consequently, scientists have been investigating intervention options based
on compounds found in edible and medicinal plants. They have had some
success, and a majority of patients with prostate cancer are now combining
the conventional therapies with these compounds as alternative,
supplementary or complementary medications.

For Kong's study, researchers used mice bred so that their immune systems
would not reject foreign biological material and injected the mice with
cells from human prostate cancer cell lines to grow tumors against which the
compounds could be tested.

"Despite convincing data from laboratory cell cultures, we knew little about
how PEITC and curcumin would perform in live animals, especially on prostate
cancer," Kong said. "So we undertook this study to evaluate how effective
PEITC and curcumin might be - individually and in combination - to prevent
and possibly treat prostate cancer."

The researchers injected the mice with curcumin or PEITC, alone or in
combination, three times a week for four weeks, beginning a day before the
introduction of the prostate cancer cells. They found the injections
significantly retarded the growth of cancerous tumors. Using PEITC and
curcumin in tandem produced even stronger effects.

The group went on to evaluate the therapeutic potential of curcumin and
PEITC in mice with well-established tumors, and the results showed that
PEITC or curcumin alone had little effect, whereas the combination of
curcumin and PEITC significantly reduced tumor growth.

The paper, "Combined Inhibitory Effects of Curcumin and Phenethyl
Isothiocyanate on the Growth of Human PC-3 Prostate Xenografts in
Immunodeficient Mice," is available at cancerres.aacrjournals.org.

The authors are Tin Oo Khor, Young-Sam Keum, Wen Lin, Jung-Hwan Kim, Rong
Hu, Guoxiang Shen, Changjiang Xu, Avanthika Gopalakrishnan, Bandaru Reddy,
Xi Zheng, Allan H. Conney and Ah-Ng Tony Kong, all from Rutgers.

WM wrote:
Every male in the universe should consider this study and add tumeric
and kale to their diet.


Don't you mean every mouse?

On 18 Jan 2006 13:48:48 -0800, "Anthony" wrote:


WM wrote:
Every male in the universe should consider this study and add tumeric
and kale to their diet.


Don't you mean every mouse?

No, only those with human cancer cells growing in their bodies.

OK then. Ignore the crap refined carbs that you eat in copious amounts
every day and the huge amounts of manufactured fats like margarine and
shortening and the overprocessed and ultra pasteurized and denatured
milk that we drink. The cigarettes that we smoke. The booze that we
drink and the huge amounts of coffee we push thru our kidneys.

Eat a bit of curry and some cauliflower and all will be well.

TC



Ken Kubos wrote:
http://ur.rutgers.edu/medrel/viewArt...ArticleID=4912

Curry and Cauliflower Could Halt Prostate Cancer

January 15, 2006

EDITOR'S NOTE: Professor Kong may be reached at 732-445-3831, ext. 226, or
e-mail . From Jan.14 through Jan. 16 only, he may be
contacted at 908-823-9251. A copy of the paper may be obtained by sending an
e-mail to .

NEW BRUNSWICK/PISCATAWAY, N.J. - Rutgers researchers have found that the
curry spice turmeric holds real potential for the treatment and prevention
of prostate cancer, particularly when combined with certain vegetables.

The scientists tested turmeric, also known as curcumin, along with phenethyl
isothiocyanate (PEITC), a naturally occurring substance particularly
abundant in a group of vegetables that includes watercress, cabbage, winter
cress, broccoli, Brussels sprouts, kale, cauliflower, kohlrabi and turnips.

"The bottom line is that PEITC and curcumin, alone or in combination,
demonstrate significant cancer-preventive qualities in laboratory mice, and
the combination of PEITC and curcumin could be effective in treating
established prostate cancers," said Ah-Ng Tony Kong, a professor of
pharmaceutics at Rutgers, The State University of New Jersey.

The discovery was announced in the Jan. 15 issue of the journal Cancer
Research by Kong and his colleagues at Rutgers' Ernest Mario School of
Pharmacy.

Prostate cancer is the second leading cause of cancer death in men in the
United States, with a half-million new cases appearing each year. The
incidence and mortality of prostate cancer have not decreased in past
decades despite tremendous efforts and resources devoted to treatment. This
is because advanced prostate cancer cells are barely responsive even to high
concentrations of chemotherapeutic agents or radiotherapy.

The authors noted that in contrast to the high incidence of prostate cancer
in the United States, the incidence of this disease is very low in India.
This has been attributed to the dietary consumption of large amounts of
plant-based foods rich in phytochemicals - nonnutritive plant chemicals that
have protective or disease-preventive properties.

Consequently, scientists have been investigating intervention options based
on compounds found in edible and medicinal plants. They have had some
success, and a majority of patients with prostate cancer are now combining
the conventional therapies with these compounds as alternative,
supplementary or complementary medications.

For Kong's study, researchers used mice bred so that their immune systems
would not reject foreign biological material and injected the mice with
cells from human prostate cancer cell lines to grow tumors against which the
compounds could be tested.

"Despite convincing data from laboratory cell cultures, we knew little about
how PEITC and curcumin would perform in live animals, especially on prostate
cancer," Kong said. "So we undertook this study to evaluate how effective
PEITC and curcumin might be - individually and in combination - to prevent
and possibly treat prostate cancer."

The researchers injected the mice with curcumin or PEITC, alone or in
combination, three times a week for four weeks, beginning a day before the
introduction of the prostate cancer cells. They found the injections
significantly retarded the growth of cancerous tumors. Using PEITC and
curcumin in tandem produced even stronger effects.

The group went on to evaluate the therapeutic potential of curcumin and
PEITC in mice with well-established tumors, and the results showed that
PEITC or curcumin alone had little effect, whereas the combination of
curcumin and PEITC significantly reduced tumor growth.

The paper, "Combined Inhibitory Effects of Curcumin and Phenethyl
Isothiocyanate on the Growth of Human PC-3 Prostate Xenografts in
Immunodeficient Mice," is available at cancerres.aacrjournals.org.

The authors are Tin Oo Khor, Young-Sam Keum, Wen Lin, Jung-Hwan Kim, Rong
Hu, Guoxiang Shen, Changjiang Xu, Avanthika Gopalakrishnan, Bandaru Reddy,
Xi Zheng, Allan H. Conney and Ah-Ng Tony Kong, all from Rutgers.

--
Ken

"Buddhism elucidates why we are sentient."
"Karma means that you don't get away with anything."