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Battle Of The Bulge: Why Losing Weight Easier Than Keeping It Off
Battle Of The Bulge: Why Losing Weight Is Easier Than Keeping It Off For
Good http://www.sciencedaily.com/releases...0108230206.htm You've successfully dropped those extra pounds only to discover that they creep back on again. Columbia University researchers may have now worked out why. In a study appearing in the December 1 issue of the Journal of Clinical Investigation, Michael Rosenbaum and colleagues from Columbia University College of Physicians and Surgeons show that body weight is regulated by coordinate metabolic, neuroendocrine, and autonomic systems that act to actually restore fat mass in individuals attempting to maintain their slim new figure. The authors suggest that our bodies interpret the weight-reduced state as one of relative deficiency in the hormone leptin. To test their hypothesis, the authors administered "replacement" doses of leptin to lean individuals that had recently lost weight as well as to obese individuals. The authors found that most of the metabolic, neuroendocrine, and autonomic changes that oppose the maintenance of a reduced body weight were actually reversed once circulating levels of leptin were restored to levels that were present prior to weight loss. These mechanisms lie at the center of why more than 85% of obese individuals that have lost weight eventually relapse. These findings suggest that therapeutics directed at the leptin signaling pathway may, pending longer studies, assist in the maintenance of reduced body weight. --------------------------------------------------------- LEPTIN .... Maybe these human studies show the real role of leptin, at last. To assist in the maintenance of reduced body weight. Maybe not.... 85 % relapse is a frightening statistic for weight loss regain ..... Yes, keeping it off is getting a little harder even after 16 months of stability after 50+ pounds loss.... and maybe it is not just the dreary winter and decreased exercise.... -- 1) Eat Till SATISFIED, Not STUFFED... Atkins repeated 9 times in the book 2) Exercise: It's Non-Negotiable..... Chapter 22 title, Atkins book 3) Don't Diet Without Supplimental Nutrients... Chapter 23 title, Atkins book 4) A sensible eating plan, and follow it. (Atkins, Self Made or Other) |
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Battle Of The Bulge: Why Losing Weight Easier Than Keeping It Off
jbuch quoted:
These findings suggest that therapeutics directed at the leptin signaling pathway may, pending longer studies, assist in the maintenance of reduced body weight. --------------------------------------------------------- LEPTIN .... Maybe these human studies show the real role of leptin, at last. To assist in the maintenance of reduced body weight. Interesting - Something that helps during maintenance and needs to be taken forever. Drug company's dream if they can come up with a patented variation. Leptin is released in our bodies in response to currently stored fat and recently eaten carbs. So folks who still have a lot to lose tend to have high leptin levels while folks with little to lose tend to have low levels (the point of the article that low body fat tends to push against maintaining). But also folks who eat too low carb for too long tend to drop leptin levels. It's why lower isn't better. Does this mean that maintenance tends to be easier for low fatters than low carbers? It could offset the losing phases being easier for plenty of low carbers. Speculation - The article appears to say that somehow our bodies take the highest amount of body fat percentage we've ever had and use that to determine relative leptin levels. If so, now to find out how to control that setting? Turn the knob, reduce your body's goal weight, what a magic bullet that would be. |
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