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Maximizing life expectancy/enjoyment



 
 
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  #1  
Old October 8th, 2003, 01:38 AM
Dr. Andrew B. Chung, MD/PhD
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Default Maximizing life expectancy/enjoyment

Ignoramus20526 wrote:

After returning from obesity to normal weight (223/177/180) due to a
eat no crap/eat less/exercise more approach, I am now thinking about
health in general. What I would like to know is, what are the things
that a person can do to maximize their life expectancy/enjoyment of
life via various natural means (no meds). I want to be clear that I
want the maximum life expectancy multiplied by enjoyment of life. So
any regimen that makes me live longer but makes me miserable is not
something that I would like to consider.

I will appreciate references to some non-kooky books that do not
advocate spending money on programs affiliated with their authors.

I am not interested in having an "extreme body", squatting 500 lbs,
etc etc. However I am interested in being fit, agile, strong, and
flexible.

My current thinking is that the cornerstone of such an approach is
doing lots of low intensity aerobic exercise such as walking, plus
calisthenics based strength training. Another cornerstone is staying
within the normal weight interval. The third cornerstone is eating
only natural and healthy food, according to some definition. To me it
means eating no heavily processed foods and no sugar. The fourth is to
have a stable life and to not work too much.

I am aware that there is some scant evidence that living on calorie
restricted diet (1500 or so calories per day all the time) also can
help one live longer. But smoehow I have a feeling that such a life is
either impossible or not satisfying to me. Right now I eat about
1900-2000 calories per day, walk 100 minutes per day, and my weight is
relatively stable for the last 3 weeks. I can live on that but not on
much less, I think.

Does anyone have any comments or book suggestions?

i


Mice live *twice* as long in captivity if they are given only half as much
as they would eat ad libitum.

Not only do they live longer but they a physically more active in their
older age. Imagine humans doubling their lifespan to 150 years and
playing tennis when they are 120 years old.

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/


  #2  
Old October 8th, 2003, 01:53 AM
Proton Soup
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Default Maximizing life expectancy/enjoyment

On Wed, 08 Oct 2003 00:46:04 GMT, wrote:

On Tue, 07 Oct 2003 20:38:32 -0400, "Dr. Andrew B. Chung, MD/PhD"
wrote:


Mice live *twice* as long in captivity if they are given only half as much
as they would eat ad libitum.

Not only do they live longer but they a physically more active in their
older age. Imagine humans doubling their lifespan to 150 years and
playing tennis when they are 120 years old.


You certainly have an active imagination. There is no objective
evidence that caloric restriction in humans would have the same effect
as in mice.


I thought there was some evidence that periodic fasting was
advantageous, prompting the body to go into a repair cycle. But maybe
that was just speculation regarding studies on mouses.

Roger

I am not an animal. I am a man.

Elephant Man


Proton Soup

  #3  
Old October 8th, 2003, 10:12 AM
Tim Tyler
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Default Maximizing life expectancy/enjoyment

In sci.med.nutrition roger wrote or quoted:
"Dr. Andrew B. Chung, MD/PhD" wrote:


Mice live *twice* as long in captivity if they are given only half as much
as they would eat ad libitum.

Not only do they live longer but they a physically more active in their
older age. Imagine humans doubling their lifespan to 150 years and
playing tennis when they are 120 years old.


You certainly have an active imagination. There is no objective
evidence that caloric restriction in humans would have the same effect
as in mice.


It almost certainly won't make us live to 150. However there's good
evidence that it will extend our lives - since it has done so in
practically every other animal tested.
--
__________
|im |yler http://timtyler.org/ Remove lock to reply.
  #4  
Old October 8th, 2003, 01:59 PM
Dr. Andrew B. Chung, MD/PhD
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Default Maximizing life expectancy/enjoyment

roger wrote:

On Tue, 07 Oct 2003 20:38:32 -0400, "Dr. Andrew B. Chung, MD/PhD"
wrote:


Mice live *twice* as long in captivity if they are given only half as much
as they would eat ad libitum.

Not only do they live longer but they a physically more active in their
older age. Imagine humans doubling their lifespan to 150 years and
playing tennis when they are 120 years old.


You certainly have an active imagination. There is no objective
evidence that caloric restriction in humans would have the same effect
as in mice.


There is no objective evidence that it won't.


Roger

I am not an animal. I am a man.

Elephant Man


He like we *are* animals. To be more precise, we like mice are mammals.

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/


  #5  
Old October 8th, 2003, 02:19 PM
Dr. Andrew B. Chung, MD/PhD
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Default Maximizing life expectancy/enjoyment

Tim Tyler wrote:

In sci.med.nutrition roger wrote or quoted:
"Dr. Andrew B. Chung, MD/PhD" wrote:


Mice live *twice* as long in captivity if they are given only half as much
as they would eat ad libitum.

Not only do they live longer but they a physically more active in their
older age. Imagine humans doubling their lifespan to 150 years and
playing tennis when they are 120 years old.


You certainly have an active imagination. There is no objective
evidence that caloric restriction in humans would have the same effect
as in mice.


It almost certainly won't make us live to 150.


That remains to be seen.

However there's good
evidence that it will extend our lives - since it has done so in
practically every other animal tested.


Correct.

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/


  #6  
Old October 8th, 2003, 03:04 PM
Philippic
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Default Maximizing life expectancy/enjoyment

"Tim Tyler" wrote in message

It almost certainly won't make us live to 150. However there's good
evidence that it will extend our lives - since it has done so in
practically every other animal tested.


Tim,

Isn't there an issue concerning *when* and *how* the individual starts their
CR regimen? IANAE, but I've heard that this is a tricky point; it's the
thing that most concerns me about 'adult-start' CR...

Ph.


  #7  
Old October 8th, 2003, 03:51 PM
Bill Lumberg
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Default Maximizing life expectancy/enjoyment

Tim Tyler wrote in message ...
In sci.med.nutrition roger wrote or quoted:
"Dr. Andrew B. Chung, MD/PhD" wrote:


Mice live *twice* as long in captivity if they are given only half as much
as they would eat ad libitum.

Not only do they live longer but they a physically more active in their
older age. Imagine humans doubling their lifespan to 150 years and
playing tennis when they are 120 years old.


You certainly have an active imagination. There is no objective
evidence that caloric restriction in humans would have the same effect
as in mice.


It almost certainly won't make us live to 150. However there's good
evidence that it will extend our lives - since it has done so in
practically every other animal tested.


I think the japanese have the highest longevity now. Perhaps we need
to sit down next to one of those 114 year old guys and write down
everything he does.
Ask him if he's keeping his lifts up?

Bill
  #8  
Old October 8th, 2003, 03:57 PM
OmegaZero2003
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Default Maximizing life expectancy/enjoyment


"Dr. Andrew B. Chung, MD/PhD" wrote in message
...
roger wrote:

On Tue, 07 Oct 2003 20:38:32 -0400, "Dr. Andrew B. Chung, MD/PhD"
wrote:


Mice live *twice* as long in captivity if they are given only half as

much
as they would eat ad libitum.

Not only do they live longer but they a physically more active in their
older age. Imagine humans doubling their lifespan to 150 years and
playing tennis when they are 120 years old.


You certainly have an active imagination. There is no objective
evidence that caloric restriction in humans would have the same effect
as in mice.


There is no objective evidence that it won't.



1) That is not how science proceeds though! Hypothesis thence evidence to
disprove or lead to refinement of the hypothesis. Science proves nothing
(every schoolboy knows - Bateson) as you should know Doc!

2) There are countless thousands of drug trials that theoretically and
clinically worked well in animal subjects but did not make it through human
trials due to mechanisms and confounding factors in humans not present in
the animals.

3) Outside medicine proper, there is no objective evidence that God does not
exist or that there are no purple kanifs on the planet that might be
circling Betelgeuse. And any of an infinite number of such hypotheses. But
science does not proceed (see 1) by trying to prove negatives.

That said, a reasonable extrapolation could be made based on the evidence of
calorie restriction in certain animals as long as "AOTBE" strictures are
observed.


  #9  
Old October 8th, 2003, 04:01 PM
OmegaZero2003
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Default Maximizing life expectancy/enjoyment


"Dr. Andrew B. Chung, MD/PhD" wrote in message
...
Tim Tyler wrote:

In sci.med.nutrition roger wrote or quoted:
"Dr. Andrew B. Chung, MD/PhD" wrote:


Mice live *twice* as long in captivity if they are given only half as

much
as they would eat ad libitum.

Not only do they live longer but they a physically more active in

their
older age. Imagine humans doubling their lifespan to 150 years and
playing tennis when they are 120 years old.

You certainly have an active imagination. There is no objective
evidence that caloric restriction in humans would have the same effect
as in mice.


It almost certainly won't make us live to 150.


That remains to be seen.

However there's good
evidence that it will extend our lives - since it has done so in
practically every other animal tested.


Correct.


AOTBE! There are a host of other factors that affect lifespan. Aneuploidy
alone will be a limiting factor!

I think you may be a bit too narrow in your extrapolation of results of
caloric restriction in animals to lifespan increases in humans. Way too
narrow.


--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/




 




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