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Exposure to Chemical Pollutants Increases Fat
http://www.scientificamerican.com/ar...tants-fat-diet
Study Finds Exposure to Chemical Pollutants Increases Fat Rats exposed to high levels of chemical pollutants in fish oil could not regulate fat properly By Sara Goodman | January 15, 2010 | 8 FAT CHEMICAL: A chemical found in fatty foods could be sentencing people to metabolic problems such as obesity and fatigue. Researchers have for the first time found a connection between exposure to certain chemicals and insulin resistance, according to a study published in the online edition of Environmental Health Perspectives. A group of European scientists examined whether exposure to persistent organic pollutants (POPs) contributed to insulin resistance, which has been increasing around the world. More than 25 percent of U.S. adults suffer from metabolic conditions stemming from insulin resistance that include fatigue, obesity and difficulty regulating blood levels of fat and sugar. Researchers fed rats a high-fat diet of either crude or refined fish oil from farmed Atlantic salmon over 28 days. The crude fish oil contained average levels of POPs that people are exposed to through fish consumption, while the refined oil contained none. Both had equal fat levels. They found that rats exposed to the crude fish oil developed belly fat and could not regulate fat properly. They had higher levels of cholesterol and several fatty acids in their livers. Those exposed to the refined fish oil experienced none of those symptoms. Researchers said the findings provide "compelling evidence" of a causal relationship between POP exposure common in the food chain and insulin resistance, and highlight the need to understand the interactions of POPs and fat-containing foods such as fish, dairy products and meat. How to deal with POPs is particularly challenging because they persist in the environment for long periods and can build up in animals' tissues. The 2001 Stockholm Convention, which the United States has ratified but not signed, lists and bans numerous POPs from manufacture and use. The researchers say their evidence reinforces the need to have international agreements aimed at limiting the release of POPs into the environment in an effort to protect public health. |
#2
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Exposure to Chemical Pollutants Increases Fat
Another instance where they should have had two other groups of rats,
both of which would be fed coconut oil rather than fish oil, one would get the POPs and one would not. My guess is that they are not familiar with the relevant literature, because it suggests that coconut oil and POPs might not present any major problem, unlike fish oil and POPs. If so, it would have been yet another good demonstration of the apparent dangers of fish oil. |
#3
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Exposure to Chemical Pollutants Increases Fat
On Jul 9, 5:08*pm, montygraham wrote:
Another instance where they should have had two other groups of rats, both of which would be fed coconut oil rather than fish oil, one would get the POPs and one would not. *My guess is that they are not familiar with the relevant literature, because it suggests that coconut oil and POPs might not present any major problem, unlike fish oil and POPs. *If so, it would have been yet another good demonstration of the apparent dangers of fish oil. Some POPs alter cells via a non-ROS mechanism. Some POPs produce reactive quinones that bind DNA. POPs tend to hyperactive Phase I enzymes which tend to produce more reactive chemicals so that they can by bound and excreted by Phase II enzymes/anti-oxidants. Reducing excess iron, proteins in addition to polyunsaturated oils should help also. |
#4
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Exposure to Chemical Pollutants Increases Fat
Study Finds Exposure to Chemical Pollutants Increases Fat
Rats exposed to high levels of chemical pollutants in fish oil could not regulate fat properly Apparently, the short-term & instant pleasure of eating processed foods concocted in the Labs of Frito-Lay outweighs long-term concerns for one's health or pocketbook MISSISSIPPI MOST OBESE STATE, COLORADO LEAST The number of obese U.S. adults rose in 16 states in the last year, helping to push obesity rates in a dozen states above 30 percent, according to a report released on Thursday. By that measure, Mississippi is the fattest state in the union with an adult obesity rate of 34.4 percent. Colorado is the least obese -- with a rate of 19.8 percent -- and the only state with an adult obesity rate below 20 percent, according to "F as in Fat," an annual report from the Trust for America's Health and the Robert Wood Johnson Foundation. While the number of states showing significant year-over-year increases in obesity has been slowing, no state chalked up an actual decline. Even Colorado does not win high marks -- its score means one in five state residents is at higher risk for conditions like heart disease and diabetes. "Today, the state with the lowest adult obesity rate would have had the highest rate in 1995," said Jeff Levi, executive director of the Trust for America's Health. Four years ago, only one U.S. state had an adult obesity rate above 30 percent, according to the report, which defines adult obesity as a having a body mass index -- a weight-to-height ratio -- of 30 or more. Over the last two decades, people in the United States have been eating less nutritious food and more of it. At the same time, activity levels have fallen, Levi said. "If we're going to reverse the obesity trends, willpower alone won't do it. We're going to have to make healthier choices easier for Americans," Levi said. Public health experts around the world have raised the alarm about exploding rates of obesity -- particularly among children -- and many are promoting efforts to encourage exercise and easier access to affordable, healthy food. In the United States -- where two-thirds of adults and nearly one- third of children are obese or overweight -- the obesity epidemic is sending healthcare costs higher and threatening everything from worker productivity to military recruitment. Some groups say such behavioral initiatives are not enough, arguing that food manufacturers and restaurant chains need limits on how they market to children. The Center for Science in the Public Interest, a U.S. consumer group, last year sued McDonald's Corp to stop the world's largest hamburger chain from using Happy Meal toys to lure children into its restaurants. Last month, the American Academy of Pediatrics -- a group of U.S. pediatricians -- called for a ban on junk food ads aimed at children. The food industry -- which has significantly increased portion sizes in restaurants and packaged foods like sugar-sweetened beverages over the last 20 years -- is fighting regulation efforts and has adopted the mantra of "personal responsibility." To that end, food and beverage companies say consumers have the right to choose what they eat and should balance their caloric intake with activity. The report released on Thursday showed that over the past 15 years, seven states have doubled their rate of obesity and 10 states have doubled their rate of diabetes. Since 1995, obesity rates have risen fastest in Oklahoma, Alabama and Tennessee, while Colorado, Connecticut and Washington, D.C., had the slowest increases. Adults from racial and ethnic minority groups, as well as those with less education and lower incomes, continue to have the highest overall obesity rates. http://www.reuters.com/article/2011/...7663JD20110707 |
#5
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Exposure to Chemical Pollutants Increases Fat
In article
, jay wrote: http://www.reuters.com/article/2011/...7663JD20110707 The report released on Thursday showed that over the past 15 years, seven states have doubled their rate of obesity and 10 states have doubled their rate of diabetes. Since 1995, obesity rates have risen fastest in Oklahoma, Alabama and Tennessee, while Colorado, Connecticut and Washington, D.C., had the slowest increases. Adults from racial and ethnic minority groups, as well as those with less education and lower incomes, continue to have the highest overall obesity rates. I just wanted to point out to the potential big-ots out there that in 2005 12.5% of Hispanics, and 25.8% of black People were poor. http://washingtonexaminer.com/news/2...gains-reversed -great-recession Economists say the Great Recession lasted from 2007 to 2009. In 2004, the median net worth of white households was $134,280, compared with $13,450 for black households, according to an analysis of Federal Reserve data by the Economic Policy Institute. By 2009, the median net worth for white households had fallen 24 percent to $97,860; the median black net worth had fallen 83 percent to $2,170, according to the EPI. Algernon Austin, director of the EPI's Program on Race, Ethnicity and the Economy, described the current wealth gap this way: "In 2009, for every dollar of wealth the average white household had, black households only had two cents." Since the end of the recession, the overall unemployment rate has fallen from 9.4 to 9.1 percent, while the black unemployment rate has risen from 14.7 to 16.2 percent, according to the Department of Labor. ---- Racism in America not only affects people financially, but it also makes them sick, because the most calories for the buck comes from nutrient poor "processed foods". The most reliable predictor of obesity in America today is a personšs wealth. http://www.nytimes.com/2007/04/22/magazine/22wwlnlede.t.html -- - Billy Mad dog Republicans to the right. Democratic spider webs to the left. True conservatives, and liberals not to be found anywhere in the phantasmagoria of the American political landscape. America is not broke. The country is awash in wealth and cash. It's just that it's not in your hands. It has been transferred, in the greatest heist in history, from the workers and consumers to the banks and the portfolios of the uber-rich. http://www.politifact.com/wisconsin/.../michael-moore /michael-moore-says-400-americans-have-more-wealth-/ |
#6
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Exposure to Chemical Pollutants Increases Fat
In article
, montygraham wrote: Another instance where they should have had two other groups of rats, both of which would be fed coconut oil rather than fish oil, one would get the POPs and one would not. My guess is that they are not familiar with the relevant literature, because it suggests that coconut oil and POPs might not present any major problem, unlike fish oil and POPs. If so, it would have been yet another good demonstration of the apparent dangers of fish oil. http://www.scientificamerican.com/ar...nsulin-resista nce-organic-pollutants-fat-diet "Researchers fed rats a high-fat diet of either crude or refined fish oil from farmed Atlantic salmon over 28 days. The crude fish oil contained average levels of POPs that people are exposed to through fish consumption, while the refined oil contained none. Both had equal fat levels." --- You can buy "organic" fish oil that will be free of "persistent organic pollutants". Why introduce "might not" and maybe, into a discussion of the results where it has no bearing? The point is: rats exposed to the crude fish oil (POPs) developed belly fat and could not regulate fat properly. They had higher levels of cholesterol and several fatty acids in their livers. Those (rats) exposed to the refined fish oil (no POPs) experienced none of those symptoms. -- - Billy Mad dog Republicans to the right. Democratic spider webs to the left. True conservatives, and liberals not to be found anywhere in the phantasmagoria of the American political landscape. America is not broke. The country is awash in wealth and cash. It's just that it's not in your hands. It has been transferred, in the greatest heist in history, from the workers and consumers to the banks and the portfolios of the uber-rich. http://www.politifact.com/wisconsin/.../michael-moore /michael-moore-says-400-americans-have-more-wealth-/ |
#7
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Exposure to Chemical Pollutants Increases Fat
In article
, jay wrote: On Jul 9, 5:08*pm, montygraham wrote: Another instance where they should have had two other groups of rats, both of which would be fed coconut oil rather than fish oil, one would get the POPs and one would not. *My guess is that they are not familiar with the relevant literature, because it suggests that coconut oil and POPs might not present any major problem, unlike fish oil and POPs. *If so, it would have been yet another good demonstration of the apparent dangers of fish oil. Some POPs alter cells via a non-ROS mechanism. Some POPs produce reactive quinones that bind DNA. POPs tend to hyperactive Phase I enzymes which tend to produce more reactive chemicals so that they can by bound and excreted by Phase II enzymes/anti-oxidants. Reducing excess iron, proteins in addition to polyunsaturated oils should help also. Do you have a citation for the above? -- - Billy Mad dog Republicans to the right. Democratic spider webs to the left. True conservatives, and liberals not to be found anywhere in the phantasmagoria of the American political landscape. America is not broke. The country is awash in wealth and cash. It's just that it's not in your hands. It has been transferred, in the greatest heist in history, from the workers and consumers to the banks and the portfolios of the uber-rich. http://www.politifact.com/wisconsin/.../michael-moore /michael-moore-says-400-americans-have-more-wealth-/ |
#8
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Exposure to Chemical Pollutants Increases Fat
On Jul 9, 8:04*pm, jay wrote:
Study Finds Exposure to Chemical Pollutants Increases Fat Rats exposed to high levels of chemical pollutants in fish oil could not regulate fat properly Apparently, the short-term & instant pleasure of eating processed foods concocted in the Labs of Frito-Lay outweighs long-term concerns for one's health or pocketbook MISSISSIPPI MOST OBESE STATE, COLORADO LEAST The number of obese U.S. adults rose in 16 states in the last year, helping to push obesity rates in a dozen states above 30 percent, according to a report released on Thursday. By that measure, Mississippi is the fattest state in the union with an adult obesity rate of 34.4 percent. Colorado is the least obese -- with a rate of 19.8 percent -- and the only state with an adult obesity rate below 20 percent, according to "F as in Fat," an annual report from the Trust for America's Health and the Robert Wood Johnson Foundation. While the number of states showing significant year-over-year increases in obesity has been slowing, no state chalked up an actual decline. Even Colorado does not win high marks -- its score means one in five state residents is at higher risk for conditions like heart disease and diabetes. "Today, the state with the lowest adult obesity rate would have had the highest rate in 1995," said Jeff Levi, executive director of the Trust for America's Health. Four years ago, only one U.S. state had an adult obesity rate above 30 percent, according to the report, which defines adult obesity as a having a body mass index -- a weight-to-height ratio -- of 30 or more. Over the last two decades, people in the United States have been eating less nutritious food and more of it. At the same time, activity levels have fallen, Levi said. "If we're going to reverse the obesity trends, willpower alone won't do it. We're going to have to make healthier choices easier for Americans," Levi said. Public health experts around the world have raised the alarm about exploding rates of obesity -- particularly among children -- and many are promoting efforts to encourage exercise and easier access to affordable, healthy food. In the United States -- where two-thirds of adults and nearly one- third of children are obese or overweight -- the obesity epidemic is sending healthcare costs higher and threatening everything from worker productivity to military recruitment. Some groups say such behavioral initiatives are not enough, arguing that food manufacturers and restaurant chains need limits on how they market to children. The Center for Science in the Public Interest, a U.S. consumer group, last year sued McDonald's Corp to stop the world's largest hamburger chain from using Happy Meal toys to lure children into its restaurants. Last month, the American Academy of Pediatrics -- a group of U.S. pediatricians -- called for a ban on junk food ads aimed at children. The food industry -- which has significantly increased portion sizes in restaurants and packaged foods like sugar-sweetened beverages over the last 20 years -- is fighting regulation efforts and has adopted the mantra of "personal responsibility." To that end, food and beverage companies say consumers have the right to choose what they eat and should balance their caloric intake with activity. The report released on Thursday showed that over the past 15 years, seven states have doubled their rate of obesity and 10 states have doubled their rate of diabetes. Since 1995, obesity rates have risen fastest in Oklahoma, Alabama and Tennessee, while Colorado, Connecticut and Washington, D.C., had the slowest increases. Adults from racial and ethnic minority groups, as well as those with less education and lower incomes, continue to have the highest overall obesity rates. http://www.reuters.com/article/2011/...7663JD20110707 The CSPI is part of the problem and no better of a solution than McDs. |
#9
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Exposure to Chemical Pollutants Increases Fat
In article
, |" wrote: On Jul 9, 8:04*pm, jay wrote: Study Finds Exposure to Chemical Pollutants Increases Fat Rats exposed to high levels of chemical pollutants in fish oil could not regulate fat properly Apparently, the short-term & instant pleasure of eating processed foods concocted in the Labs of Frito-Lay outweighs long-term concerns for one's health or pocketbook MISSISSIPPI MOST OBESE STATE, COLORADO LEAST The number of obese U.S. adults rose in 16 states in the last year, helping to push obesity rates in a dozen states above 30 percent, according to a report released on Thursday. By that measure, Mississippi is the fattest state in the union with an adult obesity rate of 34.4 percent. Colorado is the least obese -- with a rate of 19.8 percent -- and the only state with an adult obesity rate below 20 percent, according to "F as in Fat," an annual report from the Trust for America's Health and the Robert Wood Johnson Foundation. While the number of states showing significant year-over-year increases in obesity has been slowing, no state chalked up an actual decline. Even Colorado does not win high marks -- its score means one in five state residents is at higher risk for conditions like heart disease and diabetes. "Today, the state with the lowest adult obesity rate would have had the highest rate in 1995," said Jeff Levi, executive director of the Trust for America's Health. Four years ago, only one U.S. state had an adult obesity rate above 30 percent, according to the report, which defines adult obesity as a having a body mass index -- a weight-to-height ratio -- of 30 or more. Over the last two decades, people in the United States have been eating less nutritious food and more of it. At the same time, activity levels have fallen, Levi said. "If we're going to reverse the obesity trends, willpower alone won't do it. We're going to have to make healthier choices easier for Americans," Levi said. Public health experts around the world have raised the alarm about exploding rates of obesity -- particularly among children -- and many are promoting efforts to encourage exercise and easier access to affordable, healthy food. In the United States -- where two-thirds of adults and nearly one- third of children are obese or overweight -- the obesity epidemic is sending healthcare costs higher and threatening everything from worker productivity to military recruitment. Some groups say such behavioral initiatives are not enough, arguing that food manufacturers and restaurant chains need limits on how they market to children. The Center for Science in the Public Interest, a U.S. consumer group, last year sued McDonald's Corp to stop the world's largest hamburger chain from using Happy Meal toys to lure children into its restaurants. Last month, the American Academy of Pediatrics -- a group of U.S. pediatricians -- called for a ban on junk food ads aimed at children. The food industry -- which has significantly increased portion sizes in restaurants and packaged foods like sugar-sweetened beverages over the last 20 years -- is fighting regulation efforts and has adopted the mantra of "personal responsibility." To that end, food and beverage companies say consumers have the right to choose what they eat and should balance their caloric intake with activity. The report released on Thursday showed that over the past 15 years, seven states have doubled their rate of obesity and 10 states have doubled their rate of diabetes. Since 1995, obesity rates have risen fastest in Oklahoma, Alabama and Tennessee, while Colorado, Connecticut and Washington, D.C., had the slowest increases. Adults from racial and ethnic minority groups, as well as those with less education and lower incomes, continue to have the highest overall obesity rates. http://www.reuters.com/article/2011/...7663JD20110707 The CSPI is part of the problem and no better of a solution than McDs. Do you have any facts, or is this just your opinion? -- - Billy Mad dog Republicans to the right. Democratic spider webs to the left. True conservatives, and liberals not to be found anywhere in the phantasmagoria of the American political landscape. America is not broke. The country is awash in wealth and cash. It's just that it's not in your hands. It has been transferred, in the greatest heist in history, from the workers and consumers to the banks and the portfolios of the uber-rich. http://www.politifact.com/wisconsin/.../michael-moore /michael-moore-says-400-americans-have-more-wealth-/ |
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Exposure to Chemical Pollutants Increases Fat
... citation for the above?
Receptor- and reactive intermediate-mediated mechanisms of teratogenesis. Drugs and environmental chemicals can adversely alter the development of the fetus at critical periods during pregnancy, resulting in death, or in structural and functional birth defects in the surviving offspring. This process of teratogenesis may not be evident until a decade or more after birth. Postnatal functional abnormalities include deficits in brain function, a variety of metabolic diseases, and cancer. Due to the high degree of fetal cellular division and differentiation, and to differences from the adult in many biochemical pathways, the fetus is highly susceptible to teratogens, typically at low exposure levels that do not harm the mother. Insights into the mechanisms of teratogenesis come primarily from animal models and in vitro systems, and involve either receptor-mediated or reactive intermediate-mediated processes. Receptor-mediated mechanisms involving the reversible binding of xenobiotic substrates to a specific receptor are exemplified herein by the interaction of the environmental chemical 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD or "dioxin") with the cytosolic aryl hydrocarbon receptor (AHR), which translocates to the nucleus and, in association with other proteins, binds to AH-responsive elements (AHREs) in numerous genes, initiating changes in gene transcription that can perturb development. Alternatively, many xenobiotics are bioactivated by fetal enzymes like the cytochromes P450 (CYPs) and prostaglandin H synthases (PHSs) to highly unstable electrophilic or free radical reactive intermediates. Electrophilic reactive intermediates can covalently (irreversibly) bind to and alter the function of essential cellular macromolecules (proteins, DNA), causing developmental anomalies. Free radical reactive intermediates can enhance the formation of reactive oxygen species (ROS), resulting in oxidative damage to cellular macromolecules and/or altered signal transduction. The teratogenicity of reactive intermediates is determined to a large extent by the balance among embryonic and fetal pathways of xenobiotic bioactivation, detoxification of the xenobiotic reactive intermediate, detoxification of ROS, and repair of oxidative macromolecular damage. PMID: 20020262 |
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