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Obesity may not be directly due to eating
Obesity may not be directly due to eating
June 3, 2008 Courtesy Cell Press and World Science staff Wheth*er you're fat or thin is only in*di*rectly de*ter*mined by your eat*ing habits, sug*gest re*search*ers who re*port new find*ings with a study us*ing worms. They found that both eat*ing and fat in worms de*pends on lev*els of a sub*stance called ser*o*to*nin in the nerv*ous sys*tem. Yet it seems the "con*trol of fat is dis*tinct from" that of eat*ing, said Ka*veh Ash*rafi of the Uni*ver*s*ity of Cal*i*for*nia, San Fran*cis*co, one of the sci*en*tists. The re*search*ers found ev*i*dence that ser*o*to*nin, which acts as a mes*sen*ger be*tween nerve cells, works through in*de*pend*ent chan*nels to con*trol wheth*er you eat ver*sus what to do with those calo*ries once you've eat*en them. "These out*puts are re*lat*ed, but they are not con*se*quenc*es of each oth*er. It's not that feed*ing is*n't im*por*tant," Ash*rafi added. The find*ings ap*pear in the June is*sue of the re*search jour*nal Cell Me*tab*o*lism. Ash*rafi sus*pects at a fun*da*men*tal lev*el the worm find*ings can be ex*trap*o*lated to hu*mans, giv*en ser*o*to*nin's an*cient ev*o*lu*tion*ary ori*gins. This in turn may mean one could de*vel*op ther*a*pies "to ma*ni*pu*late fat me*tab*o*lism in*de*pend*ently of what you eat," he said. "Now, the fo*cus is pri*marily on feed*ing be*hav*ior. As im*por*tant as that is, it's only part of the sto*ry. it may be one rea*son di*ets fail." While fat regula*t*ion is at one lev*el a rel*a*tively sim*ple bal*ance be*tween en*er*gy in*take and out*put, the phys*i*ol*o*gy is none*the*less quite com*plex, Ash*rafi said. The re*search*ers at*tempted to dis*sect that com*plex*ity us*ing the worm C. el*e*gans, which is much sim*pler to work with than mam*mals. They found in the worms that ser*o*to*nin's con*trol of eat*ing in*volves mo*le*cules not needed for fat con*trol. Its ef*fects on fat de*pend on a sep*a*rate neu*ral chan*nel and mo*le*cules that spark sig*nals lead*ing to the break*down of fat, Ash*rafi said; the byprod*ucts of that pro*cess then come "full cir*cle" and gov*ern feed*ing be*hav*ior. The find*ings show that, as in mam*mals, C. el*e*gans eat*ing de*pends on both in*ter*nal and en*vi*ron*men*tal cues, the re*search*ers wrote: "feed*ing be*hav*ior and fat me*tab*o*lism are co*or*di*nated but in*de*pend*ent re*sponses of the nerv*ous sys*tem to the per*cep*tion of nu*tri*ent avail*abil*ity." |
#2
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Obesity may not be directly due to eating
This is why Good calories, bad calories by Taubes should be required
reading in any class about dieting or nutrition. On Thu, 05 Jun 2008 16:08:45 -0400, FOB wrote: Obesity may not be directly due to eating June 3, 2008 Courtesy Cell Press and World Science staff Wheth*er you're fat or thin is only in*di*rectly de*ter*mined by your eat*ing habits, sug*gest re*search*ers who re*port new find*ings with a study us*ing worms. They found that both eat*ing and fat in worms de*pends on lev*els of a sub*stance called ser*o*to*nin in the nerv*ous sys*tem. Yet it seems the "con*trol of fat is dis*tinct from" that of eat*ing, said Ka*veh Ash* rafi of the Uni*ver*s*ity of Cal*i*for*nia, San Fran*cis*co, one of the sci*en*tists. The re*search*ers found ev*i*dence that ser*o*to*nin, which acts as a mes*sen*ger be*tween nerve cells, works through in*de*pend*ent chan*nels to con*trol wheth*er you eat ver*sus what to do with those calo*ries once you've eat*en them. "These out*puts are re*lat*ed, but they are not con*se*quenc*es of each oth*er. It's not that feed*ing is*n't im*por*tant," Ash*rafi added. The find*ings ap*pear in the June is*sue of the re*search jour*nal Cell Me*tab*o*lism. Ash*rafi sus*pects at a fun*da*men*tal lev*el the worm find*ings can be ex*trap*o*lated to hu*mans, giv*en ser*o*to*nin's an*cient ev*o*lu*tion* ary ori*gins. This in turn may mean one could de*vel*op ther*a*pies "to ma*ni*pu*late fat me*tab*o*lism in*de*pend*ently of what you eat," he said. "Now, the fo* cus is pri*marily on feed*ing be*hav*ior. As im*por*tant as that is, it's only part of the sto*ry. it may be one rea*son di*ets fail." While fat regula*t*ion is at one lev*el a rel*a*tively sim*ple bal*ance be*tween en*er*gy in*take and out*put, the phys*i*ol*o*gy is none*the* less quite com*plex, Ash*rafi said. The re*search*ers at*tempted to dis*sect that com*plex*ity us*ing the worm C. el*e*gans, which is much sim*pler to work with than mam*mals. They found in the worms that ser*o*to*nin's con*trol of eat*ing in*volves mo*le*cules not needed for fat con*trol. Its ef*fects on fat de*pend on a sep*a*rate neu*ral chan*nel and mo*le*cules that spark sig*nals lead*ing to the break*down of fat, Ash*rafi said; the byprod*ucts of that pro*cess then come "full cir*cle" and gov*ern feed*ing be*hav*ior. The find*ings show that, as in mam*mals, C. el*e*gans eat*ing de*pends on both in*ter*nal and en*vi*ron*men*tal cues, the re*search*ers wrote: "feed*ing be*hav*ior and fat me*tab*o*lism are co*or*di*nated but in*de*pend*ent re*sponses of the nerv*ous sys*tem to the per*cep*tion of nu*tri*ent avail*abil*ity." -- Using Opera's revolutionary e-mail client: http://www.opera.com/mail/ |
#3
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Obesity may not be directly due to eating
On Jun 6, 7:13*am, Bob wrote:
This is why Good calories, bad calories by Taubes should be required * reading in any class about dieting or nutrition. Also, the fact that obesity depends on metabolic issues should come as no surprise. We all know people who can eat relatively large amounts of most everything and still remain thin. And others who have trouble keepin weight off though eating much less and doing similar activity. On Thu, 05 Jun 2008 16:08:45 -0400, FOB * wrote: Obesity may not be directly due to eating June 3, 2008 Courtesy Cell Press and World Science staff Wheth*er you're fat or thin is only in*di*rectly de*ter*mined by your eat*ing habits, sug*gest re*search*ers who re*port new find*ings with a study us*ing worms. They found that both eat*ing and fat in worms de*pends on lev*els of a sub*stance called ser*o*to*nin in the nerv*ous sys*tem. Yet it seems the "con*trol of fat is dis*tinct from" that of eat*ing, said Ka*veh Ash* rafi of the Uni*ver*s*ity of Cal*i*for*nia, San Fran*cis*co, one of the sci*en*tists. The re*search*ers found ev*i*dence that ser*o*to*nin, which acts as a mes*sen*ger be*tween nerve cells, works through in*de*pend*ent chan*nels * to con*trol wheth*er you eat ver*sus what to do with those calo*ries once * you've eat*en them. "These out*puts are re*lat*ed, but they are not con*se*quenc*es of each oth*er. It's not that feed*ing is*n't im*por*tant," Ash*rafi added. The find*ings ap*pear in the June is*sue of the re*search jour*nal Cell Me*tab*o*lism. Ash*rafi sus*pects at a fun*da*men*tal lev*el the worm find*ings can be ex*trap*o*lated to hu*mans, giv*en ser*o*to*nin's an*cient ev*o*lu*tion* ary ori*gins. This in turn may mean one could de*vel*op ther*a*pies "to ma*ni*pu*late * fat me*tab*o*lism in*de*pend*ently of what you eat," he said. "Now, the fo* cus is pri*marily on feed*ing be*hav*ior. As im*por*tant as that is, it's * only part of the sto*ry. it may be one rea*son di*ets fail." While fat regula*t*ion is at one lev*el a rel*a*tively sim*ple bal*ance be*tween en*er*gy in*take and out*put, the phys*i*ol*o*gy is none*the* less quite com*plex, Ash*rafi said. The re*search*ers at*tempted to dis*sect * that com*plex*ity us*ing the worm C. el*e*gans, which is much sim*pler to work with than mam*mals. They found in the worms that ser*o*to*nin's con*trol of eat*ing in*volves mo*le*cules not needed for fat con*trol. Its ef*fects on fat de*pend on a sep*a*rate neu*ral chan*nel and mo*le*cules that spark sig*nals lead*ing * to the break*down of fat, Ash*rafi said; the byprod*ucts of that pro*cess * then come "full cir*cle" and gov*ern feed*ing be*hav*ior. The find*ings show that, as in mam*mals, C. el*e*gans eat*ing de*pends on both in*ter*nal and en*vi*ron*men*tal cues, the re*search*ers wrote: "feed*ing be*hav*ior and fat me*tab*o*lism are co*or*di*nated but in*de*pend*ent re*sponses of the nerv*ous sys*tem to the per*cep*tion of nu*tri*ent avail*abil*ity." -- Using Opera's revolutionary e-mail client:http://www.opera.com/mail/- Hide quoted text - - Show quoted text - |
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