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OT - Study: Differential vascular dysfunction in response to diets of differing macronutrient composition: a phenomenonological study



 
 
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  #1  
Old June 16th, 2007, 04:38 PM posted to alt.support.diet.low-carb
Roger Zoul
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Posts: 1,790
Default OT - Study: Differential vascular dysfunction in response to diets of differing macronutrient composition: a phenomenonological study

Conclusions

Vascular dysfunction resulting from consumption of a high-fat or combined
relatively high-fat/high-CHO diet occurs through different physiological
processes, which may be attributable to their differing macronutrient
compositions. Combining potentially atherogenic macronutrients induces more
extensive vascular impairment than that of high-fat alone, and may be
attributable to the more marked dyslipidaemia observed with such a diet.
Thus, these findings help clarify the role of dietary components in vascular
impairment, which has implications for clinical approaches to preventing
cardiovascular disease.

http://www.nutritionandmetabolism.com/content/4/1/15



Here is the conclusion from the full paper:

Conclusion
The limitations of this study, therefore, revolve around the fact that the
nutrient
contents of the diets were not sufficiently controlled to draw very precise
conclusions
regarding their comparative effects. We cannot know whether their
differential
effects on vascular function were direct effects of nutrient content or
indirect effects
of resulting adiposity and/or circulating lipids. However, this study does
show that
high-energy diets of varying compositions can induce vascular dysfunction to
varying
degrees in the rat via mechanisms involving different layers of the vascular
wall. The
combination of high-fat and high-carbohydrate diets may be particularly
damaging,
possibly through increased hyperlipidaemia.



  #2  
Old June 16th, 2007, 06:15 PM posted to alt.support.diet.low-carb
ibmoments
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Posts: 1
Default OT - Study: Differential vascular dysfunction in response to diets of differing macronutrient composition: a phenomenonological study

On Jun 16, 8:38 am, "Roger Zoul" wrote:
Conclusions

Vascular dysfunction resulting from consumption of a high-fat or combined
relatively high-fat/high-CHO diet occurs through different physiological
processes, which may be attributable to their differing macronutrient
compositions. Combining potentially atherogenic macronutrients induces more
extensive vascular impairment than that of high-fat alone, and may be
attributable to the more marked dyslipidaemia observed with such a diet.
Thus, these findings help clarify the role of dietary components in vascular
impairment, which has implications for clinical approaches to preventing
cardiovascular disease.

http://www.nutritionandmetabolism.com/content/4/1/15

Here is the conclusion from the full paper:

Conclusion
The limitations of this study, therefore, revolve around the fact that the
nutrient
contents of the diets were not sufficiently controlled to draw very precise
conclusions
regarding their comparative effects. We cannot know whether their
differential
effects on vascular function were direct effects of nutrient content or
indirect effects
of resulting adiposity and/or circulating lipids. However, this study does
show that
high-energy diets of varying compositions can induce vascular dysfunction to
varying
degrees in the rat via mechanisms involving different layers of the vascular
wall. The
combination of high-fat and high-carbohydrate diets may be particularly
damaging,
possibly through increased hyperlipidaemia.


Weird stuff man!

 




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