If this is your first visit, be sure to check out the FAQ by clicking the link above. You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. |
|
|
Thread Tools | Display Modes |
#31
|
|||
|
|||
Maximizing life expectancy/enjoyment
Physicians do that. Then they treat prostate cancer with
anti-testosterone drugs. Fwiw, castrated men as a general rule do not get prostate cancer. -- Dr. Andrew B. Chung, MD/PhD Note: I am NOT commenting on the masturbation the topic; rather, I commenting on the alleged/oversimplified relationship of testosterone to prostate cancer. I'd be careful with this topic. While it is true anti-testosterone drugs or castration are used tp slow prostate cancer, the risk of prostate cancer (PC) in uncastrated male is increased in those males with a low testosterone to estrogen ratio. That is to say some prostate cancers are a result of physicians to refusing to treat this ratio thru ignorance or bias. Prehen, R.T. "On the prevention and therapy of prostate cancer by androgen administration." Cancer Res. 1999; 59 (17): 4164-4164. Testosterone helps maintain cellular differentiation of prostate cells. Recall with time PC adapt to the low androgen levels and their growth rate will start to increase. PC is also increased in dark skinned males with compromised vitamin D status (if one can make a small leap in logic). And of course if one looks at the animal research, it blazingly clear that a moderately high selenium status helps prevent PC. And don't forget lycopene......... The fact that castrated males don't get prostate cancer proves little other than that their prostates are either under-developed or have undergone atrophy. The book you need to read is "Anabolic therapy in Modern Medicine" by William N. Taylor, M.D. This isn't a popular press book rather it written at the physician level. He has been a researcher and author on this topic for at least 20 years. This is an excellent book. Beating the drum................ Playing the flute................. And wishing that "Saint" Augustine's father was castrated at birth.............................. ...............William A. Noyes |
#32
|
|||
|
|||
Maximizing life expectancy/enjoyment
And what drugs might those be? I suspect you don't know what you're talking about. Flutamide comes to mind as an antiandrogen. What else? Estrogens. .............LHRH agonists, Ketocanzole................... Fwiw, castrated men as a general rule do not get prostate cancer. Neither do men with genetic 5alpha-reductase deficiency. And Proscar is listed as an antiandrogen in my book:-) It competitively inhibits 5-alpha reductase. I fear you are making the same mistake that Doc Chung seems to be making............a direct simple link of prostate cancer to androgens. Some theories, some truths, some facts.......... ...........................................William A. Noyes |
#33
|
|||
|
|||
Maximizing life expectancy/enjoyment
"William A. Noyes" wrote:
And what drugs might those be? I suspect you don't know what you're talking about. Flutamide comes to mind as an antiandrogen. What else? Estrogens. ............LHRH agonists, Ketocanzole................... Fwiw, castrated men as a general rule do not get prostate cancer. Neither do men with genetic 5alpha-reductase deficiency. And Proscar is listed as an antiandrogen in my book:-) It competitively inhibits 5-alpha reductase. Chung said, "they treat prostate cancer with anti-testosterone drugs." Anti-androgen does not equal anti-testosterone, does it? Reducing 5-alpha reductase activity reduces conversion to DHT, thus increasing circulating T, right? That was my point. You might also want to review recent studies that indicate that finasteride, while good for BPH, may not be good for prostate cancer. I fear you are making the same mistake that Doc Chung seems to be making............a direct simple link of prostate cancer to androgens. Some theories, some truths, some facts.......... The link between DHT in prostate tissues and BPH is pretty strong. They are currently discovering that the positive effect of DHT reduction on BPH doesn't necessarily carry over to prostate cancer, and it may even by counterproductive. My point is that Chung's concept of reducing testosterone to treat prostate cancer is a very "old school" approach and may be contrary to what the patient needs. It's not quite on the level of stone-tool trepanation, but for him to make such a statement backed by the "I'm a physician" bit is good reason to tell him to stick to cardiology and not dip into urology and endocrinology. |
#34
|
|||
|
|||
Maximizing life expectancy/enjoyment
"John M. Williams" wrote in message ... "William A. Noyes" wrote: And what drugs might those be? I suspect you don't know what you're talking about. Flutamide comes to mind as an antiandrogen. What else? Estrogens. ............LHRH agonists, Ketocanzole................... Fwiw, castrated men as a general rule do not get prostate cancer. Neither do men with genetic 5alpha-reductase deficiency. And Proscar is listed as an antiandrogen in my book:-) It competitively inhibits 5-alpha reductase. Chung said, "they treat prostate cancer with anti-testosterone drugs." Anti-androgen does not equal anti-testosterone, does it? Reducing 5-alpha reductase activity reduces conversion to DHT, thus increasing circulating T, right? That was my point. You might also want to review recent studies that indicate that finasteride, while good for BPH, may not be good for prostate cancer. I fear you are making the same mistake that Doc Chung seems to be making............a direct simple link of prostate cancer to androgens. Some theories, some truths, some facts.......... The link between DHT in prostate tissues and BPH is pretty strong. They are currently discovering that the positive effect of DHT reduction on BPH doesn't necessarily carry over to prostate cancer, and it may even by counterproductive. My point is that Chung's concept of reducing testosterone to treat prostate cancer is a very "old school" approach and may be contrary to what the patient needs. It's not quite on the level of stone-tool trepanation, but for him to make such a statement backed by the "I'm a physician" bit is good reason to tell him to stick to cardiology and not dip into urology and endocrinology. Thank John. I still getting myself up to speed on the topic. In short, I agree with your comments to extent I understand the topic. Note please that I have other comments is this discussion. I even suggested the book Chung needs to read. The book is "Anabolic Therapy in Modern Medicine" by William N. Taylor, M.D. Given his speciality, he should read the Part 4 chapter 18 entitled "Rationale for Anabolic Therapy in Cardiovascular Diseases and Cardiac Rehabilitation":-) A good book, a warm fire, and a sleeping hound............................................. ........ ................................William A. Noyes |
#35
|
|||
|
|||
Maximizing life expectancy/enjoyment
"Dr. Andrew B. Chung, MD/PhD" wrote in message ... Tim Tyler wrote: In sci.med.nutrition Dr. Andrew B. Chung, MD/PhD wrote or quoted: DRS wrote: Did you know that in medical circles prostate cancer is known as the priest's disease? It's true. Speaking as a physician, it is not true. Risk of prostate cancer is higher in folks with higher testosterone levels. Testosterone levels tend to be higher in folks that masturbate (or are otherwise sexually active) than folks who aren't. Sorry. Are you assuming testosterone is the *only* risk factor? Is that what I have written? That is unlikely to be the case. Correct. However, we do treat prostate cancer with anti-testosterone drugs that achieve chemical castration. The action buys the patient some time but it isn't a cure. Moreover, prostate cancer is virtually unheard of in castrated males. This is a non-sequiter for a non-castrated males as this view over-simplifies the situation. The result of this view that many physicians refuse to use testosterone therapy to improve the patient's quality life and quanitity of life. However, I don't think prostate cancer /is/ known as the priest's disease ;-) I know it isn't, writing as a physician. -- Dr. Andrew B. Chung, MD/PhD |
#36
|
|||
|
|||
Maximizing life expectancy/enjoyment
"William A. Noyes" wrote:
"John M. Williams" wrote: "William A. Noyes" wrote: And what drugs might those be? I suspect you don't know what you're talking about. Flutamide comes to mind as an antiandrogen. What else? Estrogens. ............LHRH agonists, Ketocanzole................... Fwiw, castrated men as a general rule do not get prostate cancer. Neither do men with genetic 5alpha-reductase deficiency. And Proscar is listed as an antiandrogen in my book:-) It competitively inhibits 5-alpha reductase. Chung said, "they treat prostate cancer with anti-testosterone drugs." Anti-androgen does not equal anti-testosterone, does it? Reducing 5-alpha reductase activity reduces conversion to DHT, thus increasing circulating T, right? That was my point. You might also want to review recent studies that indicate that finasteride, while good for BPH, may not be good for prostate cancer. I fear you are making the same mistake that Doc Chung seems to be making............a direct simple link of prostate cancer to androgens. Some theories, some truths, some facts.......... The link between DHT in prostate tissues and BPH is pretty strong. They are currently discovering that the positive effect of DHT reduction on BPH doesn't necessarily carry over to prostate cancer, and it may even by counterproductive. My point is that Chung's concept of reducing testosterone to treat prostate cancer is a very "old school" approach and may be contrary to what the patient needs. It's not quite on the level of stone-tool trepanation, but for him to make such a statement backed by the "I'm a physician" bit is good reason to tell him to stick to cardiology and not dip into urology and endocrinology. Thank John. I still getting myself up to speed on the topic. In short, I agree with your comments to extent I understand the topic. Note please that I have other comments is this discussion. I even suggested the book Chung needs to read. The book is "Anabolic Therapy in Modern Medicine" by William N. Taylor, M.D. Given his speciality, he should read the Part 4 chapter 18 entitled "Rationale for Anabolic Therapy in Cardiovascular Diseases and Cardiac Rehabilitation":-) I would take Taylor with a grain of salt. He likes to pat himself on the back for sidestepping the recommendations of the AMA and leading the anti-steroid witch hunt which resulted in the Anabolic Steroid Act of 1990, the law that criminalized anabolic-androgenic steroids. Check out the article I wrote for Mesomorphosis a few years ago, and note the multiple footnote references to his writings: http://www.mesomorphosis.com/article...teroids-01.htm (http://tinyurl.com/qyln) |
#37
|
|||
|
|||
Maximizing life expectancy/enjoyment
Thank John. I still getting myself up to speed on the topic. In short, I agree with your comments to extent I understand the topic. Note please that I have other comments is this discussion. I even suggested the book Chung needs to read. The book is "Anabolic Therapy in Modern Medicine" by William N. Taylor, M.D. Given his speciality, he should read the Part 4 chapter 18 entitled "Rationale for Anabolic Therapy in Cardiovascular Diseases and Cardiac Rehabilitation":-) I would take Taylor with a grain of salt. He likes to pat himself on the back for sidestepping the recommendations of the AMA and leading the anti-steroid witch hunt which resulted in the Anabolic Steroid Act of 1990, the law that criminalized anabolic-androgenic steroids. Check out the article I wrote for Mesomorphosis a few years ago, and note the multiple footnote references to his writings: http://www.mesomorphosis.com/article...-anabolic-ster oids-01.htm (http://tinyurl.com/qyln) He has a point of view. His sidestepping of those old AMA recommendations are right or at least righter than.........not doing so. If he did lead these regulationist activities, I will suspect him trying to control turf and income for his profession. Such an action would be wrong and in fact immoral, IMO. Interesting article, Thank you. I see some books recommended/offered for sale on the site. Would any these be of use to this middle aged life- extension minded male? My interest is in lower levels doses than those of a weight lifter. Second question, how many use the dermal gel route of administration in this setting? Another book to buy............. ...................William A. Noyes |
Thread Tools | |
Display Modes | |
|
|
Similar Threads | ||||
Thread | Thread Starter | Forum | Replies | Last Post |
Maximizing life expectancy/enjoyment | Roger Zoul | General Discussion | 310 | October 23rd, 2003 11:19 AM |
Maximizing life expectancy/enjoyment | rosie read and post | Low Carbohydrate Diets | 189 | October 23rd, 2003 11:19 AM |
Maximizing life expectancy/enjoyment | Roger Zoul | Low Carbohydrate Diets | 4 | October 13th, 2003 06:03 PM |
Maximizing life expectancy/enjoyment | Anthony | Low Carbohydrate Diets | 2 | October 7th, 2003 10:58 PM |