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Splenda tablets - Why can't Johnson & Johnson sell them in the US?



 
 
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  #71  
Old March 21st, 2004, 07:50 PM
Matti Narkia
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Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?

Sun, 21 Mar 2004 02:54:16 +0200 in article
Matti Narkia
wrote:

Here is the abstract of a very recent toxicology review of Stevia:

Geuns JM.
Stevioside.
Phytochemistry. 2003 Nov;64(5):913-21.
PMID: 14561506 [PubMed - in process]
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=145615 06&dopt=Abstract

Laboratory of Plant Physiology, Catholic University of Leuven, Kasteelpark
Arenberg 31, B 3001 Leuven, Belgium.

Abstract:

"Stevioside is a natural sweetener extracted from leaves of
Stevia rebaudiana (Bertoni) Bertoni. The literature about
Stevia, the occurrence of its sweeteners, their biosynthetic
pathway and toxicological aspects are discussed. Injection
experiments or perfusion experiments of organs are considered as
not relevant for the use of Stevia or stevioside as food, and
therefore these studies are not included in this review. The
metabolism of stevioside is discussed in relation with the
possible formation of steviol. Different mutagenicity studies as
well as studies on carcinogenicity are discussed. Acute and
subacute toxicity studies revealed a very low toxicity of Stevia
and stevioside. Fertility and teratogenicity studies are
discussed as well as the effects on the bio-availability of
other nutrients in the diet. The conclusion is that Stevia and
stevioside are safe when used as a sweetener. It is suited for
both diabetics, and PKU patients, as well as for obese persons
intending to lose weight by avoiding sugar supplements in the
diet. No allergic reactions to it seem to exist."


I happen to have the full text of the above review article in PDF form,
which I could lend to interested individuals, please contact me by email.
Below the references from the full text article:

References

Alves et al., 1979. L.M. Alves and M. Ruddat, The presence of gibberelling
A20 in Stevia rebaudiana and its significance for the biological activity of
steviol. Plant Cell Physiol. 20 (1979), pp. 123–130.

Akashi and Yokoyama, 1975. H. Akashi and Y. Yokoyama, Security of dried-leaf
extracts of Stevia. Toxicological tests. Food Industry 18 (1975), pp. 34–43.

Anonymous, 1996. Anonymous, 1996. Voedingsaanbevelingen voor België,
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Phytochemistry 14 (1975), pp. 1741–1748. Abstract | Abstract + References |
PDF (810 K)

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de Oliveira et al., 1999. B.H. de Oliveira, M.C. dos Santos and P.C. Leal,
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737–741. Abstract | Full Text + Links | PDF (128 K)

Gardana et al., 2003. Gardana, C., Simonetti, P., Canzi, E., Zanchi, R.,
Pietta, P.G. Metabolism of stevioside and rebaudioside A from Stevia
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299–319.

Geuns et al. in press a. Geuns, J.M.C., Augustijns, P., Mols, R., Buyse,
J.G., Driessen, B. Metabolism of stevioside in pigs and intestinal
absorption characteristics of Stevioside, Rebaudioside A and Steviol. Food
Chem. Toxicol. (in press a).

Geuns et al., 2003b. J.M.C. Geuns, R.D. Malheiros, V.M.B. Moraes, E.M.-P.
Decuypere, F. Compernolle and J.G. Buyse, Metabolism of stevioside by
chickens. J. Agric. Food Chem. 51 (2003), pp. 1095–1101.

Geuns et al., in press b. Geuns, J.M.C., Bruggeman, V., and Buyse, J.G.
Effect of stevioside and steviol on the developing broiler embryos. J.
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Links | PDF (452 K)

Hagiwara et al., 1984. A. Hagiwara, S. Fukushima and M. Kitaori, Effects of
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Hersenhorn et al., 1997. J. Hersenhorn, M. Zohar, B. Crammer, Z. Ziv, V.
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pp. 173–178.

Hutapea et al., 1997. A.M. Hutapea, C. Toskulkao, D. Buddhasukh, P. Wilairat
and T. Glinsukon, Digestion of Stevioside, a Natural Sweetener, by Various
Digestive Enzymes. J. Clin. Biochem. Nutr. 23 (1997), pp. 177–186.

Hutapea et al., 1999. A.M. Hutapea, C. Toskulkao, P. Wilairat and D.
Buddhasukh, High-performance liquid chromatographic separation and
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Huxtable, 2002. R.J. Huxtable, Pharmacology and toxicology of stevioside,
rebaudioside A, and steviol. In: A.D. Kinghorn, Editor, Stevia, the Genus
Stevia. Medicinal and Aromatic Plants––Industrial Profiles, Vol. 19, Taylor
and Francis, London and NY (2002), pp. 160–177.

Kennelly, E.J., 2002. E.J. Kennelly, Sweet and non-sweet constituents of
Stevia rebaudiana (Bertoni) Bertoni. In: A.D. Kinghorn, Editor, Stevia, the
Genus Stevia. Medicinal and Aromatic Plants––Industrial Profiles, Vol. 19,
Taylor and Francis, London and NY (2002), pp. 68–85.

Kinghorn, A.D., 2002. A.D. Kinghorn, Overview. In: A.D. Kinghorn, Editor,
Stevia, the Genus Stevia. Medicinal and Aromatic Plants––Industrial
Profiles, Vol. 19, Taylor and Francis, London and NY (2002), pp. 1–17.

Kim et al., 1996a. K.K. Kim, H. Yama****a, Y. Sawa and H. Shibata, A high
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of Stevia rebaudiana Bertoni. Biosc. Biotech. Biochem. 60 (1996), pp.
685–686.

Kim et al., 1996b. K.K. Kim, Y. Sawa and H. Shibata, Hydroxylation of
ent-kaurenoic acid to steviol in Stevia rebaudiana Bertoni––purification and
partial characterization of the enzyme. Arch. Biochem. Biophys. 332 (1996),
pp. 223–230. Abstract | PDF (177 K)

Kim et al., 2002. J. Kim, Y.H. Choi and Y.-H. Choi, Use of stevioside and
cultivation of Stevia rebaudiana in Korea. In: A.D. Kinghorn, Editor,
Stevia, the Genus Stevia. Medicinal and Aromatic Plants––Industrial
Profiles, Vol. 19, Taylor and Francis, London and NY (2002), pp. 196–202.

Klongpanichpak et al., 1997. S. Klongpanichpak, C. Toskulkao, P. Temcharoen,
S. Apibal and T. Glinsukon, Lack of mutagenicity of stevioside and steviol
in Salmonella typhimurium TA 98 and TA100. J. Med. Assoc. Thailand 80
(1997), pp. 121–128.

Koyama et al., 2001. Koyama, E., Kitazawa, K., Ohori, Y., Sakai, N., Izawa,
O., Kakegawa, K., Fujino, A., Ui, M., 2001. Intestinal degradation,
absorption, and hepatic metabolism of the glycosidic sweeteners, Stevia
mixture. In: Proceedings second IUPA-International Symposium on Sweeteners,
Hiroshima, p.12.

Koyama et al., 2003a. E. Koyama, K Kitazawa, Y Ohori, O. Izawa, K. Kakegawa,
A. Fujino and M. Ui, In vitro metabolism of the glycosidic sweeteners,
Stevia mixture and enzymatically modified Stevia in human intestinal
microflora. Food Chem. Toxicol. 41 (2003), pp. 359–374. Abstract | Full Text
+ Links | PDF (379 K)

Koyama et al., 2003b. E. Koyama, N. Sakai, Y Ohori, K Kitazawa, O. Izawa, K.
Kakegawa, A. Fujino and M. Ui, Absorption and metabolism of the glycosidic
sweeteners, Stevia related compounds in human and rat. Food Chem. Toxicol.
41 (2003), pp. 875–883. Abstract | Full Text + Links | PDF (325 K)

Liu et al., 2003. J.-C. Liu, P.-K. Kao, P. Chan, Y.-H. Hsu, C.-C. Hou, G.-S.
Lien, M.-H. Hsieh, Y.-J. Chen and J.-T. Cheng, Mechanism of the
antihypertensive effect of stevioside in anesthesized dogs. Pharmacology 67
(2003), pp. 14–20.

Matsui et al., 1996a. M. Matsui, K. Matsui, Y. Kawasaki, Y. Oda, T. Noguchi,
Y. Kitagawa, M. Sawada, M. Hayashi, T. Nohmi, K. Yoshihira, M. Ishidate and
T. Sofuni, Evaluation of the Genotoxicity of Stevioside and Steviol using
six in vitro and one in vivo Mutagenicity Assays. Mutagenesis 11 (1996), pp.
573–579.

Matsui et al., 1996b. M. Matsui, T. Sofuni and T. Nohmi, Regionally-targeted
mutagenesis by metabolically-activated steviol: DNA sequence analysis of
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Abstract | Full Text + Links | PDF (98 K)

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PDF (331 K)

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158–165.


--
Matti Narkia
  #72  
Old March 22nd, 2004, 01:48 AM
Debbie Cusick
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Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?


"jamie" wrote in message
...

Did you ever try it (NOW) after they enhanced the refinement? As I
recall, when we both first tried it, it was a pale tan powder, with a
disagreeable aftertaste. Later they refined it to a bright white powder,
and I find it very acceptable to mix with other sweeteners.


I did try the NOW white powder. I was able to tolerate it in pumpkin pie,
where the various spices helped mask the taste, but for other things I still
found the taste too strong.

Debbie


  #73  
Old March 22nd, 2004, 01:39 PM
Nico Kadel-Garcia
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Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?


"sprudil" wrote in message
news:qdM6c.109554$Up2.74269@pd7tw1no...

"Julie Bove" wrote in message
...




"hba1c" wrote in message
om...
As you may know, Splenda is available in a tablet form in many
countries.


snip

I didn't know, but I would also have no use for them. If I do use

Splenda,
it is in cooking. Couldn't use tablets there!

--
Type 2
http://users.bestweb.net/~jbove/



Of course you can. just crush them.


Or dissolve it in a spoonful of warm water before stirriing it in: crushing
those wienie tablets without *sproinging* them across the kitchen is a bit
of an adventure.


  #74  
Old March 22nd, 2004, 03:54 PM
Dr. Andrew B. Chung, MD/PhD
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Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?

Nico Kadel-Garcia wrote:

"sprudil" wrote in message
news:qdM6c.109554$Up2.74269@pd7tw1no...

"Julie Bove" wrote in message
...




"hba1c" wrote in message
om...
As you may know, Splenda is available in a tablet form in many
countries.

snip

I didn't know, but I would also have no use for them. If I do use

Splenda,
it is in cooking. Couldn't use tablets there!

--
Type 2
http://users.bestweb.net/~jbove/



Of course you can. just crush them.


Or dissolve it in a spoonful of warm water before stirriing it in: crushing
those wienie tablets without *sproinging* them across the kitchen is a bit
of an adventure.


Or simply buy the powder form.

Servant to the humblest person in the universe,

Andrew

--
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Board-Certified Cardiologist
http://www.heartmdphd.com/

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Who is the humblest person in the universe?
http://makeashorterlink.com/?W1F522557

What is all this about?
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Is this spam?
http://makeashorterlink.com/?N69721867


  #75  
Old March 22nd, 2004, 08:34 PM
tintinet
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Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?

"Dr. Andrew B. Chung, MD/PhD" wrote in message ws.com...
Nico Kadel-Garcia wrote:

"sprudil" wrote in message
news:qdM6c.109554$Up2.74269@pd7tw1no...

"Julie Bove" wrote in message
...




"hba1c" wrote in message
om...
As you may know, Splenda is available in a tablet form in many
countries.

snip

I didn't know, but I would also have no use for them. If I do use

Splenda,
it is in cooking. Couldn't use tablets there!

--
Type 2
http://users.bestweb.net/~jbove/



Of course you can. just crush them.


Or dissolve it in a spoonful of warm water before stirriing it in: crushing
those wienie tablets without *sproinging* them across the kitchen is a bit
of an adventure.


Or simply buy the powder form.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD


Ah, but that would defeat the purpose!
  #76  
Old March 22nd, 2004, 08:40 PM
Bob in CT
external usenet poster
 
Posts: n/a
Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?

On 22 Mar 2004 12:34:30 -0800, tintinet wrote:

"Dr. Andrew B. Chung, MD/PhD" wrote in message
ws.com...
Nico Kadel-Garcia wrote:

"sprudil" wrote in message
news:qdM6c.109554$Up2.74269@pd7tw1no...

"Julie Bove" wrote in message
...




"hba1c" wrote in message
om...
As you may know, Splenda is available in a tablet form in many
countries.

snip

I didn't know, but I would also have no use for them. If I do use

Splenda,
it is in cooking. Couldn't use tablets there!

--
Type 2
http://users.bestweb.net/~jbove/



Of course you can. just crush them.

Or dissolve it in a spoonful of warm water before stirriing it in:

crushing
those wienie tablets without *sproinging* them across the kitchen is

a bit
of an adventure.


Or simply buy the powder form.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD


Ah, but that would defeat the purpose!


But the powdered form has maltodextrin or maltodextrin and dextrose, and
it has a nasty aftertaste.

--
Bob in CT
Remove ".x" to reply
  #77  
Old March 22nd, 2004, 09:10 PM
Denise
external usenet poster
 
Posts: n/a
Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?

I just sent them an email asking "when" the tablets would be available
due to the inconvenience of either toting your own packets or a
restaurant not having splenda. Maybe if we all do that it will spark
something?
denise
"Debbie Cusick" wrote in message ...
"hba1c" wrote in message
om...
As you may know, Splenda is available in a tablet form in many
countries.
If enough people contacted Johnson & Johnson, maybe they would start
selling them here.


I have not asked for tablets, but I have written to J&J multiple times
asking for a liquid version of Splenda (to avoid all the added maltodextrin
filler in the splenda powder) but every time I have gotten back a canned
response that "there is no market for it". I suspect I'd get the same
response about the tablets.

Debbie

  #78  
Old March 23rd, 2004, 02:31 AM
tintinet
external usenet poster
 
Posts: n/a
Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?

"Debbie Cusick" wrote in message ...
"hba1c" wrote in message
om...
As you may know, Splenda is available in a tablet form in many
countries.
If enough people contacted Johnson & Johnson, maybe they would start
selling them here.


I have not asked for tablets, but I have written to J&J multiple times
asking for a liquid version of Splenda (to avoid all the added maltodextrin
filler in the splenda powder) but every time I have gotten back a canned
response that "there is no market for it". I suspect I'd get the same
response about the tablets.

Debbie


BS, there's no market! They are just control freaks!
  #79  
Old March 23rd, 2004, 06:03 AM
Mack©®
external usenet poster
 
Posts: n/a
Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?

you are responding to a known quack and usenet kook and troll


On 22 Mar 2004 12:34:30 -0800, (tintinet) wrote:

"Dr. Andrew B. Chung, MD/PhD" wrote in message ws.com...
Nico Kadel-Garcia wrote:

"sprudil" wrote in message
news:qdM6c.109554$Up2.74269@pd7tw1no...

"Julie Bove" wrote in message
...




"hba1c" wrote in message
om...
As you may know, Splenda is available in a tablet form in many
countries.

snip

I didn't know, but I would also have no use for them. If I do use

Splenda,
it is in cooking. Couldn't use tablets there!

--
Type 2
http://users.bestweb.net/~jbove/



Of course you can. just crush them.

Or dissolve it in a spoonful of warm water before stirriing it in: crushing
those wienie tablets without *sproinging* them across the kitchen is a bit
of an adventure.


Or simply buy the powder form.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD


Ah, but that would defeat the purpose!


  #80  
Old March 24th, 2004, 06:38 PM
hba1c
external usenet poster
 
Posts: n/a
Default Splenda tablets - Why can't Johnson & Johnson sell them in the US?

BS, there's no market! They are just control freaks!

If they would sell the tablets and or liquid to me at the wholesale
price (the price they sell them to distributors in other countries), I
would be glad to set up a mail order business to tap into that "no
market".
 




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